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Mitotic Spindle Apparatus

Known as: Mitotic apparatus, Apparatus, Mitotic Spindle, Mitotic Spindles 
A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules. [GOC… Expand
National Institutes of Health

Papers overview

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Review
2007
Review
2007
The mitotic spindle is the macromolecular machine that segregates chromosomes to two daughter cells during mitosis. The major… Expand
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Review
2005
Review
2005
Abnormal chromosome content — also known as aneuploidy — is the most common characteristic of human solid tumours. It has… Expand
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Highly Cited
2003
Highly Cited
2003
Aurora-A is an oncogenic kinase essential for mitotic spindle assembly. It is activated by phosphorylation and by the microtubule… Expand
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Highly Cited
2001
Highly Cited
2001
We discovered that many proteins located in the kinetochore outer domain, but not the inner core, are depleted from kinetochores… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND In cells lacking centrosomes, the microtubule-organizing activity of the centrosome is substituted for by the combined… Expand
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Highly Cited
1999
Highly Cited
1999
Small molecules that perturb specific protein functions are valuable tools for dissecting complex processes in mammalian cells. A… Expand
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Highly Cited
1998
Highly Cited
1998
Progression of the cell cycle and control of apoptosis (programmed cell death) are thought to be intimately linked processes… Expand
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Highly Cited
1996
Highly Cited
1996
NuMA is a nuclear protein during interphase but redistributes to the spindle poles early in mitosis. To investigate its role… Expand
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Highly Cited
1996
Highly Cited
1996
Functional nuclei and mitotic spindles are shown to assemble around DNA-coated beads incubated in Xenopus egg extracts. Bipolar… Expand
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Highly Cited
1995
Highly Cited
1995
We have isolated a human homolog of Xenopus Eg5, a kinesin-related motor protein implicated in the assembly and dynamics of the… Expand
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