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Mitotic Spindle Apparatus

Known as: Mitotic apparatus, Apparatus, Mitotic Spindle, Mitotic Spindles 
A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules. [GOC… Expand
National Institutes of Health

Papers overview

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Review
2005
Review
2005
Abnormal chromosome content — also known as aneuploidy — is the most common characteristic of human solid tumours. It has… Expand
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Highly Cited
2003
Highly Cited
2003
The centrosome is the major microtubule-organizing centre of animal cells and through its influence on the cytoskeleton is… Expand
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Highly Cited
2003
Highly Cited
2003
The proper segregation of sister chromatids in mitosis depends on bipolar attachment of all chromosomes to the mitotic spindle… Expand
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Highly Cited
2002
Highly Cited
2002
The E2F transcription factor family is known to play a key role in the timely expression of genes required for cell cycle… Expand
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Highly Cited
2002
Highly Cited
2002
Aurora-A is a serine-threonine kinase implicated in the assembly and maintenance of the mitotic spindle. Here we show that human… Expand
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Highly Cited
1999
Highly Cited
1999
Chromosomes are segregated by two antiparallel arrays of microtubules arranged to form the spindle apparatus. During cell… Expand
Highly Cited
1999
Highly Cited
1999
Small molecules that perturb specific protein functions are valuable tools for dissecting complex processes in mammalian cells. A… Expand
Highly Cited
1998
Highly Cited
1998
Progression of the cell cycle and control of apoptosis (programmed cell death) are thought to be intimately linked processes… Expand
Highly Cited
1995
Highly Cited
1995
We have isolated a human homolog of Xenopus Eg5, a kinesin-related motor protein implicated in the assembly and dynamics of the… Expand
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Highly Cited
1995
Highly Cited
1995
p21CIP1/WAF1 is a CDK inhibitor regulated by the tumor suppressor p53 and is hypothesized to mediate G1 arrest. p53 has been… Expand
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