Centrosome

Known as: Centrosomes 
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Chromosomal instability (CIN) is a hallmark of many tumours and correlates with the presence of extra centrosomes. However, a… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Centrosome amplification is a common feature of many cancer cells, and it has been previously proposed that centrosome… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
Review
2007
Review
2007
Centrosomes, which were first described in the late 19th century, are found in most animal cells and undergo duplication once… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2003
Highly Cited
2003
The centrosome is the major microtubule-organizing centre of animal cells and through its influence on the cytoskeleton is… (More)
  • figure 1
  • figure 3
  • figure 2
  • table 1
Is this relevant?
Review
2002
Review
2002
Many human tumours show centrosome aberrations, indicating an underlying deregulation of centrosome structure, duplication or… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Earlier studies of invasive breast tumors have shown that 60-80% are aneuploid and approximately 80% exhibit amplified… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Review
2002
Review
2002
Centrosomes of animal cells and spindle pole bodies of fungi are the major microtubule nucleating centers. Recent studies… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2000
Highly Cited
2000
BACKGROUND In cells lacking centrosomes, the microtubule-organizing activity of the centrosome is substituted for by the combined… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Genetic instability is a common feature of many human cancers. This condition is frequently characterized by an abnormal number… (More)
  • figure I
  • figure 2
  • figure 3
  • table I
  • table 2
Is this relevant?
Highly Cited
1996
Highly Cited
1996
The centrosome plays a vital role in mitotic fidelity, ensuring establishment of bipolar spindles and balanced chromosome… (More)
Is this relevant?