Skip to search formSkip to main contentSkip to account menu

Centrosome

Known as: Centrosomes 
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Chromosomal instability (CIN) is a hallmark of many tumours and correlates with the presence of extra centrosomes. However, a… 
Highly Cited
2007
Highly Cited
2007
Many cancer-associated genes remain to be identified to clarify the underlying molecular mechanisms of cancer susceptibility and… 
Highly Cited
2003
Highly Cited
2003
The centrosome is the major microtubule-organizing centre of animal cells and through its influence on the cytoskeleton is… 
Review
2002
Review
2002
  • E. Nigg
  • Nature Reviews Cancer
  • 2002
  • Corpus ID: 9038803
Many human tumours show centrosome aberrations, indicating an underlying deregulation of centrosome structure, duplication or… 
Highly Cited
2002
Highly Cited
2002
Earlier studies of invasive breast tumors have shown that 60–80% are aneuploid and ≈80% exhibit amplified centrosomes. In this… 
Highly Cited
1999
Highly Cited
1999
Although the number of pathologies known to arise from the inappropriate folding of proteins continues to grow, mechanisms… 
Highly Cited
1998
Highly Cited
1998
Genetic instability is a common feature of many human cancers. This condition is frequently characterized by an abnormal number… 
Highly Cited
1996
Highly Cited
1996
The centrosome plays a vital role in mitotic fidelity, ensuring establishment of bipolar spindles and balanced chromosome… 
Review
1994
Review
1994
  • G. Schatten
  • Developmental biology
  • 1994
  • Corpus ID: 41256402
Neither the restoration of the centrosome during fertilization nor its reduction during gametogenesis is fully understood, but… 
Highly Cited
1984
Highly Cited
1984
Microtubules are involved in the morphogenesis of most cells and are the structural basis of the mitotic spindle. We report here…