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Centrosome

Known as: Centrosomes 
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
The centriole is an ancient microtubule-based organelle with a conserved nine-fold symmetry. Centrioles form the core of… Expand
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Review
2018
Review
2018
Aurora kinases are serine/threonine kinases essential for the onset and progression of mitosis. Aurora members share a similar… Expand
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Review
2018
Review
2018
Fertilizable eggs develop from diploid precursor cells termed oocytes. Once every menstrual cycle, an oocyte matures into a… Expand
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Review
2017
Review
2017
Abstract Male infertility is an increasing problem partly due to inherited genetic variations. Mutations in genes involved in… Expand
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Review
2017
Review
2017
The process of cellular differentiation requires the distinct spatial organization of the microtubule cytoskeleton, the… Expand
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Highly Cited
2009
Highly Cited
2009
Chromosomal instability (CIN) is a hallmark of many tumours and correlates with the presence of extra centrosomes. However, a… Expand
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Highly Cited
2003
Highly Cited
2003
The centrosome is the major microtubule-organizing centre of animal cells and through its influence on the cytoskeleton is… Expand
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Highly Cited
2003
Highly Cited
2003
Stem cell self-renewal can be specified by local signals from the surrounding microenvironment, or niche. However, the relation… Expand
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Review
2002
Review
2002
  • E. Nigg
  • Nature Reviews Cancer
  • 2002
  • Corpus ID: 9038803
Many human tumours show centrosome aberrations, indicating an underlying deregulation of centrosome structure, duplication or… Expand
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Highly Cited
1996
Highly Cited
1996
The centrosome plays a vital role in mitotic fidelity, ensuring establishment of bipolar spindles and balanced chromosome… Expand
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