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Proximal location of mouse prostate epithelial stem cells
- A. Tsujimura, Y. Koikawa, +7 authors E. Wilson
- Biology, Medicine
- The Journal of cell biology
- 24 June 2002
Stem cells are believed to regulate normal prostatic homeostasis and to play a role in the etiology of prostate cancer and benign prostatic hyperplasia. We show here that the proximal region of mouse… Expand
Conventional multiple or microdissection testicular sperm extraction: a comparative study.
BACKGROUND Testicular sperm extraction (TESE) with ICSI is becoming the first-line treatment for non-obstructive azoospermia (NOA). Recently, the sperm retrieval rate (SRR) by microdissection TESE… Expand
Single nucleotide polymorphisms in the protamine-1 and -2 genes of fertile and infertile human male populations.
- H. Tanaka, Y. Miyagawa, A. Tsujimura, K. Matsumiya, A. Okuyama, Y. Nishimune
- Biology, Medicine
- Molecular human reproduction
- 1 February 2003
Although various genetic factors have been implicated in human male infertility, the causative genes for the different types of idiopathic male infertility have not been elucidated. Protamines, which… Expand
Prediction of successful outcome of microdissection testicular sperm extraction in men with idiopathic nonobstructive azoospermia.
PURPOSE Microsurgical techniques in testicular sperm extraction can improve sperm retrieval in patients with nonobstructive azoospermia (NOA). However, spermatozoa retrieval rates have still been… Expand
Increased infiltration of tumor associated macrophages is associated with poor prognosis of bladder carcinoma in situ after intravesical bacillus Calmette-Guerin instillation.
PURPOSE Tumor associated macrophages can regulate the growth of various cancers positively or negatively. Intravesical bacillus Calmette-Guerin instillation is now gold standard treatment for bladder… Expand
Single-nucleotide polymorphisms and mutation analyses of the TNP1 and TNP2 genes of fertile and infertile human male populations.
- Y. Miyagawa, H. Nishimura, +5 authors H. Tanaka
- Biology, Medicine
- Journal of andrology
- 12 November 2005
Previously, we examined the relationship between protamine gene variations and human male infertility. In this study, we show specific variability in the transition nuclear protein genes (TNPs) of… Expand
Salvage microdissection testicular sperm extraction after failed conventional testicular sperm extraction in patients with nonobstructive azoospermia.
PURPOSE TESE is considered the best procedure for identifying a tubule for spermatozoa retrieval. This technique improves the SRR to around 50%. However, it has been unclear whether it is useful in… Expand
Clinical comparison of successful and failed microdissection testicular sperm extraction in patients with nonmosaic Klinefelter syndrome.
OBJECTIVES Testicular sperm extraction (TESE), together with intracytoplasmic sperm injection, has become the treatment of choice for patients with nonobstructive azoospermia related to nonmosaic… Expand
Transplantation of spermatogonial stem cells isolated from leukemic mice restores fertility without inducing leukemia.
More than 70% of patients survive childhood leukemia, but chemotherapy and radiation therapy cause irreversible impairment of spermatogenesis. Although autotransplantation of germ cells holds promise… Expand
Laparoscopic nephroureterectomy for upper tract transitional cell carcinoma: comparison of laparoscopic and open surgery.
- M. Tsujihata, N. Nonomura, A. Tsujimura, K. Yoshimura, Y. Miyagawa, A. Okuyama
- European urology
- 1 February 2006
OBJECTIVES We made a comparative study of laparoscopic nephroureterectomy (LNU) and standard open surgery (ONU) for upper urinary tract transitional cell carcinoma. METHODS AND METHODS From July… Expand