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Aggresome

A ubiquitin-rich cytoplasmic inclusion encased in vimentin found near the microtubule organizing center. It is formed in response to cellular… 
National Institutes of Health

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2 relations
CentrosomeCytoplasm

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
The activation sequence of cellular protein handling systems after proteasomal inhibition in dopaminergic cells.
Highly Cited
2011
Highly Cited
2011
Alzheimer's Disease‐Associated Ubiquilin‐1 Regulates Presenilin‐1 Accumulation and Aggresome Formation
The Alzheimer's disease (AD)‐associated ubiquilin‐1 regulates proteasomal degradation of proteins, including presenilin (PS). PS… 
2011
2011
Cyclosporin-A-induced prion protein aggresomes are dynamic quality-control cellular compartments
Despite the activity of cellular quality-control mechanisms, subsets of mature and newly synthesized polypeptides fail to fold… 
2009
2009
The physiologic aggresome mediates cellular inactivation of iNOS
Nitric Oxide (NO), produced by inducible nitric oxide synthase (iNOS), has been implicated in the pathogenesis of various… 
Highly Cited
2008
Highly Cited
2008
Prolyl hydroxylase PHD3 activates oxygen-dependent protein aggregation.
The HIF prolyl hydroxylases (PHDs/EGLNs) are central regulators of the molecular responses to oxygen availability. One isoform… 
Highly Cited
2005
Highly Cited
2005
Evidence for p62 aggregate formation: Role in cell survival
Highly Cited
2005
Highly Cited
2005
Rotenone induces aggregation of γ-tubulin protein and subsequent disorganization of the centrosome: Relevance to formation of inclusion bodies and neurodegeneration
Highly Cited
2005
Highly Cited
2005
Dendritic Cell Aggresome-Like-Induced Structure Formation and Delayed Antigen Presentation Coincide in Influenza Virus-Infected Dendritic Cells1
Influenza virus infection induces maturation of murine dendritic cells (DCs), which is most important for the initiation of an… 
Highly Cited
2002
Highly Cited
2002
The Mallory body as an aggresome: in vitro studies.
Prior in vivo studies supported the concept that Mallory bodies (MBs) are aggresomes of cytokeratins 8 and 18. However, to test… 
Review
1996
Review
1996
For Protein Misassembly, It's the “I” Decade
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