Kinetochores

Known as: Kinetochore 
Large multiprotein complexes that bind the centromeres of the chromosomes to the microtubules of the mitotic spindle during metaphase in the cell… (More)
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Segregation of the replicated genome during cell division in eukaryotes requires the kinetochore to link centromeric DNA to… (More)
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Highly Cited
2006
Highly Cited
2006
The microtubule-binding interface of the kinetochore is of central importance in chromosome segregation. Although kinetochore… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND To test current models for how unattached and untense kinetochores prevent Cdc20 activation of the anaphase-promoting… (More)
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Review
2003
Review
2003
The centromere is a chromosomal locus that ensures delivery of one copy of each chromosome to each daughter at cell division… (More)
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Highly Cited
2003
Highly Cited
2003
The Aurora/Ipl1 family of protein kinases plays multiple roles in mitosis and cytokinesis. Here, we describe ZM447439, a novel… (More)
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Highly Cited
2003
Highly Cited
2003
The proper segregation of sister chromatids in mitosis depends on bipolar attachment of all chromosomes to the mitotic spindle… (More)
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Highly Cited
2002
Highly Cited
2002
How sister kinetochores attach to microtubules from opposite spindle poles during mitosis (bi-orientation) remains poorly… (More)
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Highly Cited
2002
Highly Cited
2002
The Aurora kinase Ipl1p plays a crucial role in regulating kinetochore-microtubule attachments in budding yeast, but the… (More)
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Highly Cited
1996
Highly Cited
1996
The spindle assembly checkpoint delays anaphase until all chromosomes are attached to a mitotic spindle. The mad (mitotic arrest… (More)
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Highly Cited
1995
Highly Cited
1995
During mitosis in Ptk1 cells anaphase is not initiated until, on average, 23 +/- 1 min after the last monooriented chromosome… (More)
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