Mitotic Metaphase

Known as: Metaphase, Metaphase Process 
The cell cycle phase, following prophase, during which chromosomes become aligned on the equatorial plate of the cell as part of a mitotic cell cycle… (More)
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
Eribulin (E7389), a synthetic analogue of halichondrin B in phase III clinical trials for breast cancer, binds to tubulin and… (More)
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Review
2004
Review
2004
The current literature is devoid of a clearcut definition of mitotic catastrophe, a type of cell death that occurs during mitosis… (More)
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Highly Cited
2002
Highly Cited
2002
Phosphorylation at a highly conserved serine residue (Ser-10) in the histone H3 tail is considered to be a crucial event for the… (More)
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Highly Cited
2000
Highly Cited
2000
The initiation of chromosome segregation at anaphase is linked by the spindle assembly checkpoint to the completion of chromosome… (More)
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Highly Cited
1999
Highly Cited
1999
The proteolysis of key regulatory proteins is thought to control progress through mitosis. Here we analyse cyclin B1 degradation… (More)
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Highly Cited
1998
Highly Cited
1998
Gene dosage variations occur in many diseases. In cancer, deletions and copy number increases contribute to alterations in the… (More)
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Highly Cited
1998
Highly Cited
1998
The spindle assembly checkpoint mechanism delays anaphase initiation until all chromosomes are aligned at the metaphase plate… (More)
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Highly Cited
1996
Highly Cited
1996
Fluorescencein situ hybridization (FISH) is an increasingly powerful tool with a variety of applications in both basic and… (More)
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Highly Cited
1992
Highly Cited
1992
Inhibition of mitosis by many drugs that bind to tubulin has been attributed to depolymerization of microtubules. However, we… (More)
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Highly Cited
1988
Highly Cited
1988
A method of in situ hybridization for visualizing individual human chromosomes from pter to qter, both in metaphase spreads and… (More)
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