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Mice, Inbred NOD
Known as:
Non Obese Diabetic Mice
, Diabetic Mice, Non-Obese
, Non Obese Diabetic Mouse
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A strain of non-obese diabetic mice developed in Japan that has been widely studied as a model for T-cell-dependent autoimmune insulin-dependent…
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National Institutes of Health
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Related topics
Related topics
7 relations
Diabetes Mellitus
Diabetes Mellitus, Experimental
Diabetes Mellitus, Insulin-Dependent
In Blood
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Broader (1)
Laboratory mice
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Cutting Edge: CD28 Controls Peripheral Homeostasis of CD4+CD25+ Regulatory T Cells 1
Q. Tang
,
K. Henriksen
,
+6 authors
J. Bluestone
Journal of Immunology
2003
Corpus ID: 29904538
CD28/B7 blockade leads to exacerbated autoimmune disease in the nonobese diabetic mouse strain as a result of a marked reduction…
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Highly Cited
2003
Highly Cited
2003
TGF-β-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
M. Belghith
,
J. Bluestone
,
Samia Barriot
,
Jérôme Mégret
,
J. Bach
,
L. Chatenoud
Nature Network Boston
2003
Corpus ID: 26301557
CD3-specific antibodies have the unique capacity to restore self-tolerance in established autoimmunity. They induce long-term…
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Highly Cited
1997
Highly Cited
1997
The Role of Fas in Autoimmune Diabetes
A. Chervonsky
,
Yi Wang
,
+4 authors
L. Matis
Cell
1997
Corpus ID: 15214054
Highly Cited
1995
Highly Cited
1995
Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse
D. Lenschow
,
Stephen K C Ho
,
+5 authors
J. Bluestone
Journal of Experimental Medicine
1995
Corpus ID: 17009296
Insulin-dependent diabetes mellitus (IDDM) is thought to be an immunologically mediated disease resulting in the complete…
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Review
1995
Review
1995
Hyperglycemia and Diabetic Kidney Disease: The Case for Transforming Growth Factor–β as a Key Mediator
K. Sharma
,
F. Ziyadeh
Diabetes
1995
Corpus ID: 13173593
Renal cells are a rich source of transforming growth factor (TGF)-β, and they serve as targets for its actions. Our hypothesis…
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Highly Cited
1993
Highly Cited
1993
Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice
M. Rapoport
,
A. Jaramillo
,
+6 authors
T. Delovitch
Journal of Experimental Medicine
1993
Corpus ID: 725558
Beginning at the time of insulitis (7 wk of age), CD4+ and CD8+ mature thymocytes from nonobese diabetic (NOD) mice exhibit a…
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Review
1992
Review
1992
The murine autoimmune diabetes model: NOD and related strains.
H. Kikutani
,
S. Makino
Advances in Immunology
1992
Corpus ID: 441051
Highly Cited
1987
Highly Cited
1987
Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells
A. Bendelac
,
C. Carnaud
,
C. Boitard
,
J. Bach
Journal of Experimental Medicine
1987
Corpus ID: 7622328
We have developed a model of syngeneic adoptive transfer for type I diabetes mellitus of NOD mice. This model consists in…
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Review
1982
Review
1982
The case for intrarenal hypertension in the initiation and progression of diabetic and other glomerulopathies.
T. Hostetter
,
H. Rennke
,
B. Brenner
American Journal of Medicine
1982
Corpus ID: 39566345
Highly Cited
1982
Highly Cited
1982
Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins
S. Baekkeskov
,
J. Nielsen
,
B. Marner
,
T. Bilde
,
J. Ludvigsson
,
Å. Lernmark
Nature
1982
Corpus ID: 1392775
Insulin-dependent diabetic (IDD) patients have a high prevalence of circulating autoantibodies against islet of Langerhans cells…
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