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Methylnitronitrosoguanidine

Known as: Nitrosomethylnitroguanidine, MNG, N'-nitro-N-nitroso-N-methylguanidine 
A pale yellow to pink colored, crystalline solid nitrosamine that turns green or orange when exposed to light and emits very toxic fumes of nitrogen… 
National Institutes of Health

Related topics

Related topics

10 relations

Broader (4)

AntimetabolitesCarcinogensNitrosoguanidinesradiomimetic agent

Narrower (2)

ENNGpropyl-N'-nitro-N-nitrosoguanidine
analogs & derivativesaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

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Highly Cited
1987
Highly Cited
1987
Influence of neighbouring base sequence on N-methyl-N'-nitro-N-nitrosoguanidine mutagenesis in the lacI gene of Escherichia coli.
Highly Cited
1981
Highly Cited
1981
Removal of O6-methylguanine from DNA of normal and xeroderma pigmentosum-derived lymphoblastoid lines
The ability to excise (repair) UV-induced pyrimidine dimers in Escherichia coli is not related to its ability to remove N-methyl… 
Highly Cited
1979
Highly Cited
1979
Quantitation of the adaptive response to alkylating agents
ESCHERICHIA COLI can acquire resistance to the lethal and mutagenic effects of alkylating agents such as N-methyl-N′-nitro… 
Highly Cited
1974
Highly Cited
1974
Induction of sister chromatid exchanges by chemical mutagens and its possible relevance to DNA repair.
Highly Cited
1974
Highly Cited
1974
Micronuclei in mouse bone-marrow cells. A simple in vivo model for the evaluation of drug-induced chromosomal aberrations.
Highly Cited
1973
Highly Cited
1973
Structural bases for function in cytochromes c. An interpretation of comparative x-ray and biochemical data.
Abstract The tertiary structures of the photosynthetic cytochrome c2 of Rhodospirillum rubrum and eucaryotic mitochondrial… 
Highly Cited
1973
Highly Cited
1973
Increased sensitivity of xeroderma pigmentosum cells to some chemical carcinogens and mutagens.
Highly Cited
1971
Highly Cited
1971
Quantitative aspects of the repair of alkylated DNA in cultured mammalian cells. I. The effect on HeLa and Chinese hamster cell survival of alkylation of cellular macromolecules.
Highly Cited
1971
Highly Cited
1971
Quantitative aspects of the repair of alkylated DNA in cultured mammalian cells. II. Non-semiconservative DNA synthesis ('repair synthesis') in HeLa and Chinese hamster cells following treatment with…
Highly Cited
1960
Highly Cited
1960
A new chemical mutagen for bacteria, 1-methyl-3-nitro-1-nitrosoguanidine.
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