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Nitrosoguanidines

Known as: Nitrosoguanidines [Chemical/Ingredient], nitrosoguanidine 
Nitrosylated derivatives of guanidine. They are used as MUTAGENS in MOLECULAR BIOLOGY research.
National Institutes of Health

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Highly Cited
2002
Highly Cited
2002
Poly(ADP-ribose) polymerase-1 (PARP-1) protects the genome by functioning in the DNA damage surveillance network. PARP-1 is also… Expand
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Highly Cited
1996
Highly Cited
1996
Selection of cells for resistance to cisplatin, a well-recognized mutagen, could result in mutations in genes involved in DNA… Expand
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Highly Cited
1994
Highly Cited
1994
The human colon tumor cell line HCT 116 is known to have a homozygous mutation in the mismatch repair gene hMLH1 on human… Expand
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Highly Cited
1994
Highly Cited
1994
Curcumin (diferuloylmethane), a yellow pigment that is obtained from the rhizomes of Curcuma longa Linn., is a major component of… Expand
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Highly Cited
1991
Highly Cited
1991
Publisher Summary This chapter describes techniques concerned with classical and molecular genetics, cell biology, and… Expand
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Highly Cited
1991
Highly Cited
1991
A mutant strain of Helicobacter pylori with weak urease activity was created by using N-methyl-N'-nitro-N-nitrosoguanidine. The… Expand
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Highly Cited
1981
Highly Cited
1981
Previous observations that platelet guanosine 3’. 5’-monophosphate (cyclic GMP) accumulation occurred during platelet aggregation… Expand
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Highly Cited
1974
Highly Cited
1970
Highly Cited
1970
1. In neutral aqueous solution N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) yields salts of nitrocyanamide as u.v.-absorbing… Expand
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Highly Cited
1967
Highly Cited
1967
WE reported1 that the subcutaneous injection of a potent mutagen2, N-methyl-N′-nitro-N-nitrosoguanidine (NG), into rats induced… Expand
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