ENNG

Known as: N-ethyl-N'-nitro-N-nitrosoguanidine, ethyl-N'-nitro-N-nitrosoguanidine 
An alkyl nitrosoguanidine with carcinogenic properties. Used to induce cancer in experimental animal models, N-ethyl-N'-nitro-N-nitrosoguanidine… (More)
National Institutes of Health

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4 relations

Broader (3)

CarcinogensMethylnitronitrosoguanidineMutagens
analogs & derivatives

Papers overview

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2003
2003
Antiperoxidative, anti-inflammatory, and antimutagenic activities of ethanol extract of the mycelium of Ganoderma lucidum occurring in South India.
Free radical mediated genetic instability is widely thought to be a major etiological factor for initiation of carcinogenesis… (More)
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Highly Cited
1995
Highly Cited
1995
Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint.
The human colon tumor cell line HCT116 is deficient in wild-type hMLH1, is defective in mismatch repair (MMR), exhibits… (More)
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Highly Cited
1995
Highly Cited
1995
Role of reciprocal exchange, one-ended invasion crossover and single-strand annealing on inverted and direct repeat recombination in yeast: different requirements for the RAD1, RAD10, and RAD52 genes…
We have constructed novel DNA substrates (one inverted and three direct repeats) based on the same 0.6-kb repeat sequence to… (More)
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1993
1993
Inhibitory effects of fucoxanthin, a natural carotenoid, on N-ethyl-N'-nitro-N-nitrosoguanidine-induced mouse duodenal carcinogenesis.
Fucoxanthin was shown to inhibit chemical carcinogenesis. Fucoxanthin is a natural carotenoid prepared from brown algae which is… (More)
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1987
1987
SOS-inducing activity of chemical carcinogens and mutagens in Salmonella typhimurium TA1535/pSK1002: examination with 151 chemicals.
The umu test system is a newly developed method to evaluate genotoxic activities of a wide variety of environmental carcinogens… (More)
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1987
1987
Induction of anchorage independence in human diploid foreskin fibroblasts by carcinogenic metal salts.
We studied whether arsenic, nickel, and chromium compounds that are human carcinogens could induce transformation of cultured… (More)
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1984
1984
Selection of strongly immunogenic "tum-" variants from tumors at high frequency using 5-azacytidine
Highly immunogenic "tum-" (non-tumorigenic in normal syngeneic hosts) clonal variants can be selected from a variety of poorly… (More)
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1983
1983
Mutagen treatment as a means for selecting immunogenic variants from otherwise poorly immunogenic malignant murine tumors.
The selection of nontumorigenic (turn'), highly immunogenic variants from four different tumorigenic but poorly immuno genic… (More)
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Highly Cited
1978
Highly Cited
1978
Correlation of anchorage-independent growth with tumorigenicity of chemically transformed mouse epidermal cells.
The BALB/c mouse primary epidermal cell culture sys tem is currently being developed as a model system for chemical… (More)
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1975
1975
A colon tumor model for anticancer agent evaluation.
Colon tumors of mice were induced with 1, 2-dimethylhydrazine, N-nitroso-N-methylurethane, methylnitrosourea, and 4-methyl-N… (More)
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