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ENNG

Known as: N-ethyl-N'-nitro-N-nitrosoguanidine, ethyl-N'-nitro-N-nitrosoguanidine 
An alkyl nitrosoguanidine with carcinogenic properties. Used to induce cancer in experimental animal models, N-ethyl-N'-nitro-N-nitrosoguanidine… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

CarcinogensMethylnitronitrosoguanidineMutagens
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1996
Highly Cited
1996
Analysis of DNA alkylation damage and repair in mammalian cells by the comet assay.
The single cell gel electrophoresis (SCGE) or comet assay, which measures DNA strand breaks in individual cells, was used to… 
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Highly Cited
1995
Highly Cited
1995
Role of reciprocal exchange, one-ended invasion crossover and single-strand annealing on inverted and direct repeat recombination in yeast: different requirements for the RAD1, RAD10, and RAD52 genes…
We have constructed novel DNA substrates (one inverted and three direct repeats) based on the same 0.6-kb repeat sequence to… 
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Highly Cited
1994
Highly Cited
1994
Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice.
Curcumin (diferuloylmethane), a yellow pigment that is obtained from the rhizomes of Curcuma longa Linn., is a major component of… 
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Review
1992
Review
1992
Anticarcinogenic effects of (-)-epigallocatechin gallate.
BACKGROUND Our research objective is to develop nontoxic cancer chemopreventive agents and to apply these agents in treating… 
Highly Cited
1989
Highly Cited
1989
Inhibitory Effect of (—)‐Epigallocatechin Gallate on Carcinogenesis with N‐Ethyl‐N′‐nitro‐N‐nitrosoguanidine in Mouse Duodenum
(—)‐Epigallocatechin gallate (EGCG) is the main polyphenolic constituent of green tea infusion and inhibits tumor promotion by… 
Highly Cited
1987
Highly Cited
1987
SOS-inducing activity of chemical carcinogens and mutagens in Salmonella typhimurium TA1535/pSK1002: examination with 151 chemicals.
The umu test system is a newly developed method to evaluate genotoxic activities of a wide variety of environmental carcinogens… 
Highly Cited
1984
Highly Cited
1984
Sensitivity of human cell strains having different abilities to repair O6-methylguanine in DNA to inactivation by alkylating agents including chloroethylnitrosoureas.
In order to investigate the mechanisms of cellular damage by alkylating agents, human fibroblasts and tumor cell strains having… 
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Highly Cited
1980
Highly Cited
1980
Possible involvement of S‐nitrosothiols in the activation of guanylate cyclase by nitroso compounds
The inhibitory effects of methemoglobin on activation of coronary arterial soluble guanylate cyclase by nitric oxide (NO… 
Highly Cited
1979
Highly Cited
1979
Isolation and characterization of Escherichia coli K-12 mutants unable to induce the adaptive response to simple alkylating agents
  • P. Jeggo
  • Journal of bacteriology
  • 1979
  • Corpus ID: 948836
When Esherichia coli cells are exposed to a low level of simple alkylating agents, they induce the adaptive response which… 
Highly Cited
1978
Highly Cited
1978
Correlation of anchorage-independent growth with tumorigenicity of chemically transformed mouse epidermal cells.
Abstract The BALB/c mouse primary epidermal cell culture system is currently being developed as a model system for chemical… 
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