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Fetal pathology in rats following uterine-vessel clamping on day 14 of gestation.
TLDR
Large blisters and hematomas at the tip of the snout may have caused tongue displacement to such an extent that palate closure was mechanically impaired, and the malformations apparently resulted secondarily from necrosis of mesenchymal tissues that had been fully differentiated. Expand
Micronuclei in mouse bone-marrow cells. A simple in vivo model for the evaluation of drug-induced chromosomal aberrations.
TLDR
The results indicate that the test is especially suitable for initial large-scale screening of suspected chromosomal mutagens and spindle poisons, and the use of the relationship between doses required to induce micronuclei and lethal doses in mice provides a practical measure of the relative potencies of such compounds. Expand
Teratological experiments with ergotamine in mice, rats, and rabbits.
TLDR
In doses that affected maternal weight gain during treatment, ergotamine produced an increase in prenatal mortality in rats and evidence of fetal retardation in all three species and a uterotonic effect may also be involved in the mechanism of action. Expand
Characteristics of the menstrual cycle in nonhuman primates. I. Similarities and dissimilarities between Macaca fascicularis and Macaca arctoides.
Comparative studies of reproductive characteristics were carried out on a colony of Macaca fascicularis and M. arctoides. Seasonal differences were not significant between species, and conceptionsExpand
Comparison of the teratogenic effects of mustine hydrochloride in rats and ferrets. The value of the ferret as an experimental animal in teratology
The teratogenic effects on the offspring of ferrets given single sc injections of mustine hydrochloride on various days of gestation is described and compared with a smaller series of rats treated atExpand
Characteristics of the menstrual cycle in nonhuman primates. I. Similarities and dissimilarities between Macaca fascicularis and Macaca arctoides.
Comparative studies of reproductive characteristics were carried out on a colony of Macaca fascicularis and M. arctoides. Seasonal differences were not significant between species, and conceptionsExpand
Collection of control data from teratological experiments on mice, rats, and rabbits. A group study.
TLDR
Comparison of the data from the various laboratories in general revealed similar results, and the variations observed are presumed to be due to differences in experimental conditions. Expand
[Pharmacological properties of acetyldigoxin-alpha].
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