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Escherichia coli mutator mutants deficient in methylation-instructed DNA mismatch correction.
  • B. Glickman, M. Radman
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1 February 1980
Our approach to the isolation of DNA mismatch-correction-deficient mutants was based upon the isolation of 2-aminopurine-resistant second-site revertants of Escherichia coli dam- mutants. We isolatedExpand
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Competition among juvenile Atlantic salmon (Salmo salar) and steelhead (Oncorhynchus mykiss): relevance to invasion potential in British Columbia
Atlantic salmon (Salmo salar) are routinely captured in both freshwater and marine environments of coastal British Columbia (Canada). Recent evidence suggests that this species is now naturallyExpand
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Patterns of somatic mutations in immunoglobulin variable genes.
The mechanism responsible for somatic mutation in the variable genes of antibodies is unknown and may differ from previously described mechanisms that produce mutation in DNA. We have analyzed 421Expand
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Evidence of natural reproduction of aquaculture-escaped Atlantic salmon in a coastal British Columbia river.
: We present evidence of the first successful natural spawning of Atlantic salmon (  Salmo salar) documented on the Pacific coast of North America. Twelve juvenile Atlantic salmon composed of twoExpand
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Human DNA repair systems: An overview
DNA repair systems act to maintain genome integrity in the face of replication errors, environmental insults, and the cumulative effects of age. More than 70 human genes directly involved in the fiveExpand
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Unique self-complementarity of palindromic sequences provides DNA structural intermediates for mutation.
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Recent Advances in Research on Radiofrequency Fields and Health: 2001–2003
The widespread use of wireless telecommunications devices, particularly mobile phones, has resulted in increased human exposure to radiofrequency (RF) fields. Although national and internationalExpand
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N-methyl-N'-nitro-N-nitrosoguanidine-induced mutation in a RecA strain of Escherichia coli.
274 N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced forward mutations in the lacI gene of an Escherichia coli RecA- strain were cloned and sequenced. Base substitutions accounted for 264Expand
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Mechanisms of spontaneous mutagenesis: an analysis of the spectrum of spontaneous mutation in the Escherichia coli lacI gene.
We have obtained via DNA sequence analysis a spectrum of 174 spontaneous mutations occurring in the lac I gene of Escherichia coli. The spectrum comprised base substitution, frameshift, deletion,Expand
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Mutational specificity of alkylating agents and the influence of DNA repair
Alkylating treatments predominantly induce G: C = > A: T transitions, consistent with the predicted significance of the miscoding potential of the O6‐alG lesion. However, the frequency andExpand
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