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MLLT4 wt Allele

Known as: CANOE, Drosophila, Homolog of Gene, FLJ34371, AFADIN 
Human MLLT4 wild-type allele is located in the vicinity of 6q27 and is approximately 145 kb in length. This allele, which encodes afadin protein, is… 
National Institutes of Health

Related topics

Related topics

13 relations
6q27AfadinCell MovementCell-Cell Adhesion Process

Broader (1)

MLLT4 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Differential regional and subcellular localization patterns of afadin splice variants in the mouse central nervous system
2016
2016
[Expression Patterns of the Proteins Associated with Cell Junctions in Mouse Testes].
OBJECTIVE To study on the expression patterns of proteins associated with cell junctions in the developing mouse testes. METHOD… 
2015
2015
A short splicing isoform of afadin suppresses the cortical axon branching in a dominant-negative manner
Suppression of surplus axon branching is crucial for formation of proper neuronal networks; however, the molecular mechanisms… 
2014
2014
Genetic Ablation of Afadin Causes Mislocalization and Deformation of Paneth Cells in the Mouse Small Intestinal Epithelium
Afadin is an actin filament-binding protein that acts cooperatively in cell adhesion with the cell adhesion molecule nectin, and… 
2014
2014
Signal Transduction The Adherens Junction Protein Afadin Is an AKT Substrate that Regulates Breast Cancer Cell Migration
The PI3K–AKT signaling pathway regulates all phenotypes that contribute to progression of human cancers, including breast cancer… 
2014
2014
Afadin controls cadherin cluster stability using clathrin-independent mechanism
Afadin is an actin-binding protein that interacts with the intracellular region of the transmembrane proteins, nectins. In… 
2013
2013
The Adherens Junction Protein Afadin Is an AKT Substrate that Regulates Breast Cancer Cell Migration
The PI3K–AKT signaling pathway regulates all phenotypes that contribute to progression of human cancers, including breast cancer… 
2013
2013
AF-6 is a positive modulator of the PINK1/parkin pathway and is deficient in Parkinson's disease
Parkin E3 ubiquitin-ligase activity and its role in mitochondria homeostasis are thought to play a role in Parkinson's disease… 
2012
2012
Afadin Is Required for Maintenance of Dendritic Structure and Excitatory Tone*
Background: Active molecular mechanisms that maintain the dendritic field of neurons are unclear. Results: Afadin maintains… 
Highly Cited
1999
Highly Cited
1999
Different behavior of l-Afadin and Neurabin-II during the formation and destruction of cell – cell adherens junction
We have recently isolated two novel actin filament-binding proteins, l-afadin and neurabin-II and shown that they are localized… 
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