Skip to search formSkip to main contentSkip to account menu

MLLT4 gene

Known as: Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated to, 4 Gene, MIXED LINEAGE LEUKEMIA, TRANSLOCATED TO, 4, MLLT4 
This gene is involved in cell adhesion and cytoskeletal modeling.
National Institutes of Health

Related topics

Related topics

10 relations
AfadinCell MovementCell-Cell Adhesion ProcessCytokinesis

Narrower (1)

MLLT4 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Differential Effects of Myocardial Afadin on Pressure Overload-Induced Compensated Cardiac Hypertrophy.
BACKGROUND Pressure overload induces cardiac hypertrophy, which often ends in heart failure. Afadin is an adaptor protein that is… 
2014
2014
Afadin controls cadherin cluster stability using clathrin-independent mechanism
Afadin is an actin-binding protein that interacts with the intracellular region of the transmembrane proteins, nectins. In… 
2013
2013
The Adherens Junction Protein Afadin Is an AKT Substrate that Regulates Breast Cancer Cell Migration
The PI3K–AKT signaling pathway regulates all phenotypes that contribute to progression of human cancers, including breast cancer… 
2012
2012
Nectins localize Willin to cell–cell junctions
Willin is a FERM‐domain protein, which is related to the Drosophila Expanded, a protein known to be a component of the Hippo… 
2010
2010
Regulation by afadin of cyclical activation and inactivation of Rap1, Rac1, and RhoA small G proteins at leading edges of moving NIH3T3 cells
2004
2004
Involvement of heterophilic trans‐interaction of Necl‐5/Tage4/PVR/CD155 with nectin‐3 in formation of nectin‐ and cadherin‐based adherens junctions
Nectins, Ca2+‐independent immunoglobulin (Ig)‐like cell–cell adhesion molecules and cadherins, Ca2+‐dependent cell–cell adhesion… 
2003
2003
The expression of nectin-1alpha in normal human skin and various skin tumours.
BACKGROUND A novel cell-cell adhesion system that consists of nectin and afadin has been identified at cadherin-based cell-cell… 
2003
2003
ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions.
Afadin is an actin filament (F-actin)-binding protein that is associated with the cytoplasmic tail of nectin, a Ca(2… 
Highly Cited
2000
Highly Cited
2000
Human nectin3/PRR3: a novel member of the PVR/PRR/nectin family that interacts with afadin.
1998
1998
Identification of Ce-AF-6, a novel Caenorhabditis elegans protein, as a putative Ras effector.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)