Afadin

Known as: Trithorax Homolog 4, AF-6 Protein, AF6 
Afadin (1824 aa, ~207 kDa) is encoded by the human MLLT4 gene. This protein is involved in both cell communication and the formation of adherens… (More)
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Junctional adhesion molecule-A (JAM-A) is a transmembrane tight junction protein that has been shown to regulate barrier function… (More)
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Highly Cited
2007
Highly Cited
2007
Par-3 is a cell-polarity protein that regulates the formation of tight junctions (TJs) in epithelial cells, where claudin is a… (More)
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Highly Cited
2006
Highly Cited
2006
The Ca2+-independent immunoglobulin-like molecule nectin first forms cell-cell adhesion and then assembles cadherin at nectin… (More)
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Highly Cited
2005
Highly Cited
2005
Adherens junctions (AJs) are a major cell-cell adhesion structure in epithelial cells that are formed by two major cell-cell… (More)
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Review
2003
Review
2003
The cadherin superfamily plays key roles in intercellular adhesion. An emerging intercellular adhesion system, consisting of… (More)
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Highly Cited
2002
Highly Cited
2002
alpha-Catenin is an integral component of adherens junctions, where it links cadherins to the actin cytoskeleton. alpha-Catenin… (More)
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Highly Cited
2001
Highly Cited
2001
Nectins are adhesion molecules that participate in the organization of epithelial and endothelial junctions and serve as… (More)
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Highly Cited
2000
Highly Cited
2000
#"%$ & ' () * + & , & -. / 102 43! & , "65 . 798 : ;< = > ? 02 @ @ &'A > . &8B 7& 8B ! C 4 & A "ED . 7#$ + GF2 * +$ + 8 "H ) G… (More)
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Highly Cited
1999
Highly Cited
1999
We recently isolated a novel actin filament (F-actin)-binding protein, afadin, that has two isoforms, l- and s-afadins. l-Afadin… (More)
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Highly Cited
1999
Highly Cited
1999
We have isolated a novel actin filament-binding protein, named afadin, localized at cadherin-based cell-cell adherens junctions… (More)
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