Skip to search formSkip to main contentSkip to account menu
You are currently offline. Some features of the site may not work correctly.

Afadin

Known as: Trithorax Homolog 4, AF-6 Protein, AF6 
Afadin (1824 aa, ~207 kDa) is encoded by the human MLLT4 gene. This protein is involved in both cell communication and the formation of adherens… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
During development, epithelial cells must generate and respond to tension without disrupting epithelial barrier function. The… 
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2009
Highly Cited
2009
Junctional adhesion molecule-A (JAM-A) is a transmembrane tight junction protein that has been shown to regulate barrier function… 
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Highly Cited
2006
Highly Cited
2006
The Ca2+-independent immunoglobulin-like molecule nectin first forms cell-cell adhesion and then assembles cadherin at nectin… 
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Review
2003
Review
2003
The cadherin superfamily plays key roles in intercellular adhesion. An emerging intercellular adhesion system, consisting of… 
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2002
Highly Cited
2002
α-Catenin is an integral component of adherens junctions, where it links cadherins to the actin cytoskeleton. α-Catenin is also… 
Highly Cited
2001
Highly Cited
2001
Nectins are adhesion molecules that participate in the organization of epithelial and endothelial junctions and serve as… 
  • figure 2
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Highly Cited
1999
Highly Cited
1999
We have isolated a novel actin filament–binding protein, named afadin, localized at cadherin-based cell–cell adherens junctions… 
  • table I
  • figure 1
  • table II
  • figure 2
  • figure 3
Highly Cited
1999
Highly Cited
1999
Afadin is an actin filament-binding protein that binds to nectin, an immunoglobulin-like cell adhesion molecule, and is… 
  • figure 1
  • figure 2
  • table I
  • figure 3
  • figure 4
Highly Cited
1999
Highly Cited
1999
We recently isolated a novel actin filament (F-actin)–binding protein, afadin, that has two isoforms, l- and s-afadins. l-Afadin… 
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
1998
Highly Cited
1998
Eph-related receptor tyrosine kinases (RTKs) have been implicated in intercellular communication during embryonic development. To… 
  • figure 1
  • table 1
  • table 2
  • table 3
  • figure 3