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MLL protein, human

Known as: KMT2A, Histone-Lysine N-Methyltransferase 2A, ALL-1 
Histone-lysine N-methyltransferase MLL (3969 aa, ~432 kDa) is encoded by the human MLL gene. This protein is involved in both histone modification… 
National Institutes of Health

Related topics

Related topics

15 relations
AT-Hook MotifsBromodomainDNA-Binding ProteinsEnzyme Gene

Broader (2)

Histone-Lysine N-MethyltransferaseMyeloid-Lymphoid Leukemia Protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Abstract 2416: Transcriptome and cluster analysis of infant acute lymphoblastic leukemia cases with and without MLL (KMT2A) rearrangement
2015
2015
NK cells play a significant role in immunosurveillance at the early stage of MLL-AF9 acute myeloid leukemia via CD226/CD155 interactions
Acute myeloid leukemia (AML) is an aggressive hematological malignancy, and the mechanism underlying immune system involvement in… 
Review
2011
Review
2011
MLLT7 (myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 7)
Review on MLLT7 (myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 7), with data on… 
Review
2011
Review
2011
MLLT10 (myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10)
Review on MLLT10 (myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10), with data on… 
2011
2011
It has become increasingly clear that fusions of MLL induce widespread epigenetic dysregulation that may mediate much of their transforming activity.