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MK-421

Known as: MK 421, MK421 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

EnalaprilEnalapril Maleate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1984
1984
Comparative studies: enalapril versus hydrochlorothiazide as first-step therapy for the treatment of primary hypertension.
1984
1984
Duration of Action and Short‐Term Hormonal Responses to Enalapril (MK 421) in Normal Subjects
Enalapril is a converting enzyme inhibitor with a prolonged duration of action. We investigated the arterial pressure and… 
Highly Cited
1983
Highly Cited
1983
Reflex‐Hemodynamic Adjustments and Baroreflex Sensitivity During Converting Enzyme Inhibition with MK‐421 in Normal Humans
Invasive hemodynamic measurements and determination of baroreflex sensitivity were carried out in 12 mildly sodium-depleted… 
1983
1983
Enalapril (MK421) in the treatment of hypertension with renal artery stenosis.
The converting enzyme inhibitor, enalapril, was given to 20 hypertensive patients with renal artery stenosis in a single daily… 
1983
1983
Novel substrates for angiotensin I converting enzyme.
1983
1983
Isolated liver granulomas of murine Schistosoma mansoni contain components of the angiotensin system.
Angiotensin I (AI) and angiotensin II/III (AII/III) were detected by radioimmunoassay in homogenates of isolated liver granulomas… 
Highly Cited
1982
Highly Cited
1982
Enalapril maleate and a lysine analogue (MK-521) in normal volunteers; relationship between plasma drug levels and the renin angiotensin system.
1 Two single doses of 10 mg each of the converting enzyme inhibitor enalapril maleate or MK-421 and of its lysine analogue (MK… 
1982
1982
Converting-enzyme inhibitor enalapril (MK421) in treatment of hypertension with renal artery stenosis.
Enalapril maleate (MK421), a new inhibitor of angiotensin converting enzyme, in single daily doses of 1.25-40 mg was assessed in… 
1982
1982
Correlation between angiotensin converting enzyme inhibition and the acute hypotensive response to MK 421 in essential hypertension.
1. The acute hormonal and hypotensive effects of MK 421 (10 mg p.o.) were assessed by a double-blind randomized trial in twelve… 
1981
1981
Angiotensin converting enzyme activity in human serum: relationship to enzyme inhibitor in vivo and in vitro.
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