MK-421

Known as: MK 421, MK421 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1985
1985
Inhibition of angiotensin II generation in the plasma does not fully explain the antihypertensive effects of converting enzyme… (More)
Is this relevant?
Highly Cited
1984
Highly Cited
1984
A number of studies have shown short-term hemodynamic and symptomatic improvement in patients with congestive heart failure… (More)
  • table I
  • table 2
  • figure 1
  • table 3
  • figure 2
Is this relevant?
1984
1984
Enalapril is a converting enzyme inhibitor with a prolonged duration of action. We investigated the arterial pressure and… (More)
Is this relevant?
1984
1984
Enalapril, the ethyl ester of a potent angiotensin converting enzyme inhibitor, enalaprilat, was administered to healthy… (More)
Is this relevant?
1983
1983
Invasive hemodynamic measurements and determination of baroreflex sensitivity were carried out in 12 mildly sodium-depleted… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 5
  • figure 3
Is this relevant?
1983
1983
Animal studies (particularly in dogs) on enalapril maleate have served to predict the patterns of absorption and elimination… (More)
Is this relevant?
1983
1983
Enalapril maleate (MK-421), an ethyl ester, is an angiotensin-converting enzyme (ACE) inhibitor from a novel series of… (More)
Is this relevant?
Highly Cited
1982
Highly Cited
1982
Nineteen hypertensive patients were treated with increasing doses of the new angiotensin-converting enzyme inhibitor MK 421… (More)
Is this relevant?
1982
1982
MK 421, at the dose of 25 mg/kg, administered daily by gavage to spontaneously hypertensive rats (SHRs) from their 4th to 15th… (More)
Is this relevant?
1981
1981
The effects of the new oral converting enzyme inhibitor "MK-421" on blood pressure, plasma renin activity, plasma angiotensin II… (More)
Is this relevant?