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Insulin resistance and cardiovascular disease.
Cardiovascular risk factors cluster in obese individuals. Insulin resistance emerges as a common pathogenetic denominator underlying the risk factor cluster. Defects in nonesterified fatty acids… Expand
US trends in prevalence, awareness, treatment, and control of hypertension, 1988-2008.
CONTEXT Hypertension is a major risk factor for cardiovascular disease and treatment and control of hypertension reduces risk. The Healthy People 2010 goal was to achieve blood pressure (BP) control… Expand
Relation of dietary fat and fiber to elevation of C-reactive protein.
We examined the relation of dietary fiber, fat, and other dietary factors to levels of highly sensitive C-reactive protein (CRP) in 4,900 adult participants in the 1999 to 2000 National Health and… Expand
Low birth weights contribute to high rates of early-onset chronic renal failure in the Southeastern United States.
- D. Lackland, H. Bendall, C. Osmond, B. Egan, D. Barker
- Archives of internal medicine
- 22 May 2000
BACKGROUND The southeastern United States is a region in which rates of cardiovascular and renal diseases are excessive. Within the Southeast, South Carolina has unusually high rates of end-stage… Expand
Therapeutic Inertia Is an Impediment to Achieving the Healthy People 2010 Blood Pressure Control Goals
- E. Okonofua, K. Simpson, Ammar Jesri, Shakaib U. Rehman, V. Durkalski, B. Egan
- 1 March 2006
Therapeutic inertia (TI), defined as the providers’ failure to increase therapy when treatment goals are unmet, contributes to the high prevalence of uncontrolled hypertension (≥140/90 mm Hg), but… Expand
Comparative efficacy and safety of aliskiren, an oral direct renin inhibitor, and ramipril in hypertension: a 6-month, randomized, double-blind trial
Objectives This double-blind study compared long-term efficacy, safety and tolerability of the oral direct renin inhibitor aliskiren and the angiotensin-converting enzyme inhibitor ramipril alone and… Expand
The CardioMetabolic Health Alliance: Working Toward a New Care Model for the Metabolic Syndrome.
- L. Sperling, J. Mechanick, +23 authors S. Grundy
- Journal of the American College of Cardiology
- 1 September 2015
The Cardiometabolic Think Tank was convened on June 20, 2014, in Washington, DC, as a "call to action" activity focused on defining new patient care models and approaches to address contemporary… Expand
Effect of a high-fiber diet vs a fiber-supplemented diet on C-reactive protein level.
- D. King, B. Egan, R. Woolson, A. Mainous, Yaser Al-Solaiman, Ammar Jesri
- Archives of internal medicine
- 12 March 2007
BACKGROUND Diets high in fiber are associated with lower levels of inflammatory markers. This study examined the reduction in inflammation from a diet supplemented with fiber compared with a diet… Expand
Prehypertension and Cardiovascular Morbidity
- Heather A Liszka, A. Mainous, D. King, C. Everett, B. Egan
- The Annals of Family Medicine
- 1 July 2005
PURPOSE The Seventh Report of the Joint National Commission (JNC 7) on High Blood Pressure established prehypertension (120 to 139 mm Hg systolic or 80 to 89 mm Hg diastolic) as a new risk category.… Expand
Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association.
Resistant hypertension (RH) is defined as above-goal elevated blood pressure (BP) in a patient despite the concurrent use of 3 antihypertensive drug classes, commonly including a long-acting calcium… Expand