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Insulin resistance and cardiovascular disease.
Cardiovascular risk factors cluster in obese individuals. Insulin resistance emerges as a common pathogenetic denominator underlying the risk factor cluster. Defects in nonesterified fatty acidsExpand
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US trends in prevalence, awareness, treatment, and control of hypertension, 1988-2008.
CONTEXT Hypertension is a major risk factor for cardiovascular disease and treatment and control of hypertension reduces risk. The Healthy People 2010 goal was to achieve blood pressure (BP) controlExpand
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Relation of dietary fat and fiber to elevation of C-reactive protein.
We examined the relation of dietary fiber, fat, and other dietary factors to levels of highly sensitive C-reactive protein (CRP) in 4,900 adult participants in the 1999 to 2000 National Health andExpand
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Low birth weights contribute to high rates of early-onset chronic renal failure in the Southeastern United States.
BACKGROUND The southeastern United States is a region in which rates of cardiovascular and renal diseases are excessive. Within the Southeast, South Carolina has unusually high rates of end-stageExpand
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Therapeutic Inertia Is an Impediment to Achieving the Healthy People 2010 Blood Pressure Control Goals
Therapeutic inertia (TI), defined as the providers’ failure to increase therapy when treatment goals are unmet, contributes to the high prevalence of uncontrolled hypertension (≥140/90 mm Hg), butExpand
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Comparative efficacy and safety of aliskiren, an oral direct renin inhibitor, and ramipril in hypertension: a 6-month, randomized, double-blind trial
Objectives This double-blind study compared long-term efficacy, safety and tolerability of the oral direct renin inhibitor aliskiren and the angiotensin-converting enzyme inhibitor ramipril alone andExpand
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The CardioMetabolic Health Alliance: Working Toward a New Care Model for the Metabolic Syndrome.
The Cardiometabolic Think Tank was convened on June 20, 2014, in Washington, DC, as a "call to action" activity focused on defining new patient care models and approaches to address contemporaryExpand
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Effect of a high-fiber diet vs a fiber-supplemented diet on C-reactive protein level.
BACKGROUND Diets high in fiber are associated with lower levels of inflammatory markers. This study examined the reduction in inflammation from a diet supplemented with fiber compared with a dietExpand
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Prehypertension and Cardiovascular Morbidity
PURPOSE The Seventh Report of the Joint National Commission (JNC 7) on High Blood Pressure established prehypertension (120 to 139 mm Hg systolic or 80 to 89 mm Hg diastolic) as a new risk category.Expand
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Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association.
Resistant hypertension (RH) is defined as above-goal elevated blood pressure (BP) in a patient despite the concurrent use of 3 antihypertensive drug classes, commonly including a long-acting calciumExpand
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