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Enalapril

Known as: Enalaprila, Enalaprilum, (S)-1-(N-(1-(Ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline 
A dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, enalapril is… 
National Institutes of Health

Related topics

Related topics

36 relations

Broader (3)

Amino Acids, CyclicAngiotensin-Converting Enzyme InhibitorsAntihypertensive Agents
AngioedemaAngiotensin-Converting Enzyme Inhibitors [MoA]Bartter DiseaseCongestive heart failure

Narrower (10)

EnacardMK-421NCX 899Renitec

Papers overview

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Highly Cited
1994
Highly Cited
1994
BLOOD PRESSURE CONTROL IN THE ANTARCTIC FISH PAGOTHENIA BORCHGREVINKI
The mechanisms of cardiovascular control in the Antarctic fish Pagothenia borchgrevinki were investigated during rest and… 
1993
1993
Effects of Atenolol and Enalapril on Kidney Function in Hypertensive Diabetic Patients
Summary: The aim of this study was to evaluate the efficacy of enalapril and atenolol in decreasing the severity of proteinuria… 
1992
1992
Endothelium‐Dependent Relaxations Are Augmented in Rats Chronically Treated with the Angiotensin‐Converting Enzyme Inhibitor Enalapril
The study was designed to evaluate the effects of chronic inhibition of angiotensin-converting enzyme (ACE) on the reactivity of… 
Review
1989
Review
1989
Fatal angioedema associated with enalapril.
: A 65-year-old male with a long history of congestive heart failure presented to the emergency room with facial swelling 7 h… 
1986
1986
The effects of enalapril on blood pressure and the kidney in normotensive subjects under altered sodium balance.
Eight healthy volunteers received both oral enalapril (EN; MK-421) 20 mg and placebo (PL) under stable conditions of sodium… 
Highly Cited
1985
Highly Cited
1985
Synthesis and pharmacology of the potent angiotensin-converting enzyme inhibitor N-[1(S)-(ethoxycarbonyl)-3-phenylpropyl]-(S)-alanyl-(S)-pyroglutamic acid.
Structure 3a, a potent angiotensin-converting enzyme inhibitor, was prepared in five steps from L-(+)-alpha-amino-4-phenylbutyric… 
Highly Cited
1984
Highly Cited
1984
Cardioprotective effects of enalapril in acute myocardial ischemia.
Enalapril, a new potent orally active angiotensin-converting enzyme inhibitor, was studied in cats subjected to acute myocardial… 
1984
1984
Hemodynamic and antihypertensive effects of the new oral angiotensin-converting-enzyme inhibitor MK-421 (enalapril).
The antihypertensive, hemodynamic, and humoral effects of the new converting-enzyme inhibitor enalapril (MK-421) were assessed by… 
1983
1983
Resolution of Captopril‐Induced Rash After Substitution of Enalapril
Angiotensin converting enzyme (ACE) inhibition is a novel and effective approach to the treatment of hypertension and congestive… 
1983
1983
Long-term clinical experience with enalapril in essential hypertension.
This study was undertaken to evaluate whether, after long-term enalapril administration tachyphylaxis to the blockade of…