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- Publications
- Influence
Defining the role of common variation in the genomic and biological architecture of adult human height
- A. Wood, T. Esko, +442 authors T. Frayling
- Biology, Medicine
- Nature Genetics
- 8 September 2014
Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different… Expand
Nonparametric Analysis of Statistic Images from Functional Mapping Experiments
- A. Holmes, R. Blair, J. Watson, I. Ford
- Computer Science, Medicine
- Journal of cerebral blood flow and metabolism…
- 1 January 1996
TLDR
Diffuse axonal injury in head injury: Definition, diagnosis and grading
- J. Adams, D. Doyle, I. Ford, T. Gennarelli, D. Graham, D. Mclellan
- Medicine
- Histopathology
- 1 July 1989
Diffuse axonal injury is one of the most important types of brain damage that can occur as a result of non‐missile head injury, and it may be very difficult to diagnose post mortem unless the… Expand
A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease
- M. Nikpay, A. Goel, +148 authors M. Farrall
- Biology, Medicine
- Nature Genetics
- 27 August 2015
Existing knowledge of genetic variants affecting risk of coronary artery disease (CAD) is largely based on genome-wide association study (GWAS) analysis of common SNPs. Leveraging phased haplotypes… Expand
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
- R. Scott, V. Lagou, +211 authors I. Barroso
- Biology, Medicine
- Nature Genetics
- 9 August 2012
Through genome-wide association meta-analyses of up to 133,010 individuals of European ancestry without diabetes, including individuals newly genotyped using the Metabochip, we have increased the… Expand
Lipoprotein-associated phospholipase A2 as an independent predictor of coronary heart disease. West of Scotland Coronary Prevention Study Group.
- C. Packard, D. O'Reilly, +9 authors G. Lowe
- Medicine
- The New England journal of medicine
- 19 October 2000
BACKGROUND
Chronic inflammation is believed to increase the risk of coronary events by making atherosclerotic plaques in coronary vessels prone to rupture. We examined blood constituents potentially… Expand
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
- C. Pattaro, A. Teumer, +249 authors C. Fox
- Biology, Medicine
- Nature communications
- 21 January 2016
Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide association studies for… Expand
Effects of exogenous melatonin on sleep: a meta-analysis.
- A. Brzezinski, M. Vangel, +4 authors I. Ford
- Psychology, Medicine
- Sleep medicine reviews
- 1 February 2005
Exogenous melatonin reportedly induces drowsiness and sleep, and may ameliorate sleep disturbances, including the nocturnal awakenings associated with old age. However, existing studies on the… Expand
Efficacy of ivabradine, a new selective I(f) inhibitor, compared with atenolol in patients with chronic stable angina.
- J. Tardif, I. Ford, M. Tendera, M. Bourassa, K. Fox
- Medicine
- European heart journal
- 1 December 2005
AIMS
Ivabradine, a new I(f) inhibitor which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent. Ivabradine has shown anti-ischaemic and… Expand
Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)
- G. Davies, N. Armstrong, +125 authors I. Deary
- Psychology, Medicine
- Molecular Psychiatry
- 1 February 2015
General cognitive function is substantially heritable across the human life course from adolescence to old age. We investigated the genetic contribution to variation in this important, health- and… Expand