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MBD4 gene

Known as: MBD4, Methyl-CpG Binding Domain Protein 4 Gene, METHYL-CpG-BINDING DOMAIN PROTEIN 4 
This gene is involved in DNA mismatch repair.
National Institutes of Health

Related topics

Related topics

9 relations
DNA RepairHydrolysisMBD4 protein, humanMBD5 gene

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MED1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Comment on Sanders et al , page 1526 MBD 4 : guardian of the epigenetic galaxy
CG dinucleotides serve as sites for cytosine modifications, beginning with the addition of a methyl group by DNA… 
2015
2015
Methyl-CpG binding domain 4 tagging polymorphisms and esophageal cancer risk in a Chinese population
In 2009, esophageal cancer was recorded as the fifth most commonly diagnosed cancer and the fourth leading cause of cancer… 
Review
2014
Review
2014
Structural and mutation studies of two DNA demethylation related glycosylases: MBD4 and TDG
Two mammalian DNA glycosylases, methyl-CpG binding domain protein 4 (MBD4) and thymine DNA glycosylase (TDG), are involved in… 
2010
2010
MBD4 gene is associated with rheumatoid arthritis in Chinese patients in Taiwan
This study examines whether or not MBD4 polymorphism is a marker for rheumatoid arthritis (RA) susceptibility or severity for… 
2009
2009
High Resolution Mapping of Cia3: A Common Arthritis Quantitative Trait Loci in Different Species1
Murine collagen induced arthritis (CIA) is a widely used model of rheumatoid arthritis (RA). Identification of CIA susceptibility… 
2008
2008
Somatic mutations in mismatch repair genes in sporadic gastric carcinomas are not a cause but a consequence of the mutator phenotype.
2008
2008
MBD4-Mediated Glycosylase Activity on a Chromatin Template Is Enhanced by Acetylation
ABSTRACT The ability of the MBD4 glycosylase to excise a mismatched base from DNA has been assessed in vitro using DNA substrates… 
2006
2006
Distinct Roles of the Steroid Receptor Coactivator 1 and of MED1 in Retinoid-induced Transcription and Cellular Differentiation*
Retinoic acid receptors (RARs) are the molecular relays of retinoid action on transcription, cellular differentiation and… 
2004
2004
DNA Methylation Profiling and Functional Assay in Mouse Embryos Development Using Methylation CpG Island Microarray(II): The Aberrant Methylation in Cloned Mice Genome (II)
Review
2003
Review
2003
Analyzing tumor suppressor activities in the murine small intestine.
We have used mice deficient in a series of genes with either known or potential tumor suppressive activity to determine the… 
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