MAP3K5 protein, human

Known as: MAP/ERK Kinase Kinase 5, mitogen-activated protein kinase kinase kinase 5, human, MEK Kinase 5 
Mitogen-activated protein kinase kinase kinase 5 (1374 aa, ~155 kDa) is encoded by the human MAP3K5 gene. This protein is involved in the apoptosis… (More)
National Institutes of Health

Papers overview

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Review
2011
Review
2011
It is well accepted that atherosclerosis occurs in a site-specific manner especially at branch points where disturbed blood flow… (More)
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2009
2009
Glucose-dependent insulinotropic polypeptide (GIP) potentiates glucose-stimulated insulin secretion, insulin biosynthesis, and… (More)
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Highly Cited
2008
Highly Cited
2008
Mutation in Cu/Zn-superoxide dismutase (SOD1) is a cause of familial amyotrophic lateral sclerosis (ALS). Mutant SOD1 protein… (More)
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Highly Cited
2008
Highly Cited
2008
This study is the first to investigate the anticancer effect of plumbagin in human melanoma A375.S2 cells. Plumbagin exhibited… (More)
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Highly Cited
2007
Highly Cited
2007
There is growing interest in the potential beneficial effects of flavonoids in the aging and diseased brain. We have investigated… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Epidemiological studies have shown gender differences in the incidence of congestive heart failure (CHF); however, the… (More)
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Highly Cited
2006
Highly Cited
2006
Pancreatic adenocarcinoma is an aggressive human malignancy and is characterized by resistance to apoptosis. Recently, NADPH… (More)
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Highly Cited
2003
Highly Cited
2003
Redox-sensing molecules such as thioredoxin (TRX) and glutaredoxin (GRX) bind to apoptosis signal-regulating kinase 1 (ASK1) and… (More)
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Review
2002
Review
2002
Cellular redox is controlled by the thioredoxin (Trx) and glutathione (GSH) systems that scavenge harmful intracellular reactive… (More)
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