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MAP Kinase Kinase Kinase 5

Known as: MAPK Kinase Kinase 5, Apoptosis Signal Regulating Kinase 1, MAPKKK5 
A 150-kDa MAP kinase kinase kinase that may play a role in the induction of APOPTOSIS. It has specificity for MAP KINASE KINASE 3; MAP KINASE KINASE… 
National Institutes of Health

Papers overview

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Review
2013
Review
2013
The thioredoxin (Trx) system is one of the central antioxidant systems in mammalian cells, maintaining a reducing environment by… 
Highly Cited
2009
Highly Cited
2009
Parkinson disease (PD)-associated genomic deletions and the destabilizing L166P point mutation lead to loss of the cytoprotective… 
Highly Cited
2006
Highly Cited
2006
Pancreatic adenocarcinoma is an aggressive human malignancy and is characterized by resistance to apoptosis. Recently, NADPH… 
Highly Cited
2006
Highly Cited
2006
Human glutathione S-transferase P1-1 (GSTP1-1) is an ubiquitously expressed protein that plays an important role in the… 
Highly Cited
2004
Highly Cited
2004
The Raf/MEK/extracellular signal-regulated kinase (ERK) signaling pathway regulates diverse cellular processes such as… 
Highly Cited
2001
Highly Cited
2001
ABSTRACT The Akt family of serine/threonine-directed kinases promotes cellular survival in part by phosphorylating and inhibiting… 
Highly Cited
2000
Highly Cited
2000
ABSTRACT We have previously shown that nerve growth factor (NGF) withdrawal-induced death requires the activity of the small GTP… 
Highly Cited
1998
Highly Cited
1998
The Fas death receptor can activate the Jun NH2-terminal kinase (JNK) pathway through the receptor-associated protein Daxx. Daxx… 
Highly Cited
1996
Highly Cited
1996
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK…