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MAP Kinase Kinase Kinase 5

Known as: MAPK Kinase Kinase 5, Apoptosis Signal Regulating Kinase 1, MAPKKK5 
A 150-kDa MAP kinase kinase kinase that may play a role in the induction of APOPTOSIS. It has specificity for MAP KINASE KINASE 3; MAP KINASE KINASE… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Generally, both endoplasmic reticulum (ER) stress and mitochondrial dysregulation are a potential therapeutic target of… Expand
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Highly Cited
2009
Highly Cited
2009
Parkinson disease (PD)-associated genomic deletions and the destabilizing L166P point mutation lead to loss of the cytoprotective… Expand
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Highly Cited
2006
Highly Cited
2006
Pancreatic adenocarcinoma is an aggressive human malignancy and is characterized by resistance to apoptosis. Recently, NADPH… Expand
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Highly Cited
2006
Highly Cited
2006
Human glutathione S-transferase P1-1 (GSTP1-1) is an ubiquitously expressed protein that plays an important role in the… Expand
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Highly Cited
2004
Highly Cited
2004
The Raf/MEK/extracellular signal-regulated kinase (ERK) signaling pathway regulates diverse cellular processes such as… Expand
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Review
2002
Review
2002
The 14-3-3 proteins are a family of phosphoserine/phosphothreonine-binding molecules that control the function of a wide array of… Expand
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Highly Cited
2001
Highly Cited
2001
ABSTRACT The Akt family of serine/threonine-directed kinases promotes cellular survival in part by phosphorylating and inhibiting… Expand
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Highly Cited
2000
Highly Cited
2000
ABSTRACT We have previously shown that nerve growth factor (NGF) withdrawal-induced death requires the activity of the small GTP… Expand
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Highly Cited
1998
Highly Cited
1998
The Fas death receptor can activate the Jun NH2-terminal kinase (JNK) pathway through the receptor-associated protein Daxx. Daxx… Expand
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Highly Cited
1996
Highly Cited
1996
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK… Expand
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