MAP Kinase Kinase Kinase

Known as: Mitogen-Activated Protein Kinase Kinase Kinases, MAPKKKs, Kinases, MAP Kinase Kinase 
Mitogen-activated protein kinase kinase kinases (MAPKKKs) are serine-threonine protein kinases that initiate protein kinase signaling cascades. They… (More)
National Institutes of Health

Papers overview

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2011
2011
Regulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinase Thorsten Gantke, Srividya Sriskantharajah… (More)
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Highly Cited
2006
Highly Cited
2006
Highwire is an extremely large, evolutionarily conserved E3 ubiquitin ligase that negatively regulates synaptic growth at the… (More)
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Highly Cited
2003
Highly Cited
2003
TAK1, a member of the mitogen-activated kinase kinase kinase (MAPKKK) family, participates in proinflammatory cellular signaling… (More)
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Highly Cited
2002
Highly Cited
2002
The signal transduction pathways that control cytokinesis in plants are largely uncharacterized. Here, we provide genetic… (More)
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Highly Cited
1999
Highly Cited
1999
In C. elegans, a Wnt/WG-like signaling pathway down-regulates the TCF/LEF-related protein, POP-1, to specify posterior cell fates… (More)
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1998
1998
The Schizosaccharomyces pombe win1-1 mutant has a defect in the G2-M transition of the cell cycle. Although the defect is… (More)
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Highly Cited
1997
Highly Cited
1997
A human homolog of the yeast Ssk2 and Ssk22 mitogen-activated protein kinase kinase kinases (MAPKKK) was cloned by functional… (More)
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Highly Cited
1996
Highly Cited
1996
The Tpl-2 protein serine/threonine kinase was originally identified, in a C-terminally deleted form, as the product of an… (More)
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1996
1996
Both angiotensin II (Ang II) and platelet-derived growth factor (PDGF) rapidly increase intracellular Ca2+ and activate protein… (More)
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1993
1993
Plasma membrane-enriched fractions were prepared from human embryonic retinal cells transformed with either adenovirus E1A and… (More)
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