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MAP Kinase Kinase Kinase

Known as: Mitogen-Activated Protein Kinase Kinase Kinases, MAPKKKs, Kinases, MAP Kinase Kinase 
Mitogen-activated protein kinase kinase kinases (MAPKKKs) are serine-threonine protein kinases that initiate protein kinase signaling cascades. They… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Mitogen-activated protein kinase (MAPK) modules play key roles in the transduction of environmental and developmental signals… Expand
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Review
2018
Review
2018
Mitogen-activated protein kinases (MAPKs) are conserved protein kinases in eukaryotes that establish signaling modules where MAPK… Expand
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Highly Cited
2009
Highly Cited
2009
Mitogen-activated protein kinase (MAPK) cascades have been identified in various signaling pathways involved in plant development… Expand
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Highly Cited
2006
Highly Cited
2006
Highwire is an extremely large, evolutionarily conserved E3 ubiquitin ligase that negatively regulates synaptic growth at the… Expand
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Highly Cited
2001
Highly Cited
2001
In mammals, TAK1, a MAPKKK kinase, is implicated in multiple signaling processes, including the regulation of NF-kappaB activity… Expand
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Highly Cited
1999
Highly Cited
1999
In C. elegans, a Wnt/WG-like signaling pathway down-regulates the TCF/LEF-related protein, POP-1, to specify posterior cell fates… Expand
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Highly Cited
1997
Highly Cited
1997
Mitogen-activated protein (MAP) kinase cascades are activated in response to various extracellular stimuli, including growth… Expand
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Highly Cited
1997
Highly Cited
1997
Exposure of the yeast Saccharomyces cerevisiae to high extracellular osmolarity induces the Sln1p-Ypd1p-Ssk1p two-component… Expand
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Highly Cited
1996
Highly Cited
1996
The Tpl‐2 protein serine/threonine kinase was originally identified, in a C‐terminally deleted form, as the product of an… Expand
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Highly Cited
1995
Highly Cited
1995
The role of mitogen-activated protein (MAP) kinase cascades in integrating distinct upstream signals was studied in yeast… Expand
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