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MAP Kinase Kinase Kinase

Known as: Mitogen-Activated Protein Kinase Kinase Kinases, MAPKKKs, Kinases, MAP Kinase Kinase 
Mitogen-activated protein kinase kinase kinases (MAPKKKs) are serine-threonine protein kinases that initiate protein kinase signaling cascades. They… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Plant defense against pathogens often includes rapid programmed cell death known as the hypersensitive response (HR). Recent… Expand
Highly Cited
2006
Highly Cited
2006
Highwire is an extremely large, evolutionarily conserved E3 ubiquitin ligase that negatively regulates synaptic growth at the… Expand
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Review
2005
Review
2005
  • M. Katoh
  • Oncology reports
  • 2005
  • Corpus ID: 30825273
WNT/planar cell polarity (PCP) signaling pathway controls tissue polarity and cell movement through the activation of RHOA, c-Jun… Expand
Highly Cited
2004
Highly Cited
2004
The Arabidopsis mitogen-activated protein kinase (MAPK) kinase 2 (MKK2) and the downstream MAPKs MPK4 and MPK6 were isolated by… Expand
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Highly Cited
1999
Highly Cited
1999
In C. elegans, a Wnt/WG-like signaling pathway down-regulates the TCF/LEF-related protein, POP-1, to specify posterior cell fates… Expand
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Highly Cited
1998
Highly Cited
1998
Tumor necrosis factor (TNF) elicits a diverse array of inflammatory responses through engagement of its type-1 receptor (TNFR1… Expand
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Highly Cited
1997
Highly Cited
1997
Mitogen-activated protein (MAP) kinase cascades are activated in response to various extracellular stimuli, including growth… Expand
Highly Cited
1997
Highly Cited
1997
Exposure of the yeast Saccharomyces cerevisiae to high extracellular osmolarity induces the Sln1p-Ypd1p-Ssk1p two-component… Expand
Highly Cited
1996
Highly Cited
1996
The Tpl‐2 protein serine/threonine kinase was originally identified, in a C‐terminally deleted form, as the product of an… Expand
Highly Cited
1995
Highly Cited
1995
The role of mitogen-activated protein (MAP) kinase cascades in integrating distinct upstream signals was studied in yeast… Expand