MAP3K5 gene

Known as: MAP/ERK KINASE KINASE 5, MAP3K5, apoptosis signal regulating kinase 1 
This gene is involved in the MAP kinase signal transduction pathway.
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Apoptosis signal-regulating kinase 1 (ASK1) plays a pivotal role in oxidative stress-induced cell death. Reactive oxygen species… (More)
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Highly Cited
2002
Highly Cited
2002
It has been shown that thioredoxin (Trx) in a reduced form binds to and inhibits apoptosis signal-regulating kinase 1 (ASK1… (More)
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Highly Cited
2001
Highly Cited
2001
Senescence is a sequence of biochemical and physiological events that constitute the final stage of development. The… (More)
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Highly Cited
2001
Highly Cited
2001
In vivo infection of lymphatic tissues by the human immunodeficiency virus type 1 (HIV-1) leads to enhanced apoptosis, which… (More)
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Highly Cited
2001
Highly Cited
2001
Apoptosis signal-regulating kinase 1 (ASK1) is a mitogen-activated protein kinase kinase kinase that can activate the c-Jun N… (More)
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Highly Cited
2001
Highly Cited
2001
The Ser/Thr kinase Raf-1 is a protooncogene product that is a central component in many signaling pathways involved in normal… (More)
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Highly Cited
2000
Highly Cited
2000
Antioxidant response element (ARE) regulates the induction of a number of cellular antioxidant and detoxifying enzymes. However… (More)
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Review
1998
Review
1998
The tumor necrosis factor receptor (TNFR) superfamily represents a growing family, with over 20 members having been identified… (More)
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Highly Cited
1998
Highly Cited
1998
The essential cellular functions associated with microtubules have led to a wide use of microtubule-interfering agents in cancer… (More)
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Highly Cited
1998
Highly Cited
1998
Apoptosis signal-regulating kinase (ASK) 1 was recently identified as a mitogen-activated protein (MAP) kinase kinase kinase… (More)
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