MADD gene

Known as: DENN, MAP-Kinase Activating Death Domain Gene, INSULINOMA-GLUCAGONOMA PROTEIN 20 
This proto-oncogene is involved in the regulation of apoptosis and propagates cell death via signal transduction.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2017
0519882017

Papers overview

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Highly Cited
2013
Highly Cited
2013
MOTIVATION Fronto-temporal dementia (FTD) and amyotrophic lateral sclerosis (ALS, also called motor neuron disease, MND) are… (More)
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Highly Cited
2012
Highly Cited
2012
The tripartite DENN module, comprised of a N-terminal longin domain, followed by DENN, and d-DENN domains, is a GDP-GTP exchange… (More)
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2012
2012
Mutations in the renal tumour suppressor protein, folliculin, lead to proliferative skin lesions, lung complications and renal… (More)
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2011
2011
The Berlin Affective Word List (BAWL, Võ, Jacobs, & Conrad, Behavior Research Methods, 35, 606-609, 2006) and the BAWL-R (Võ et… (More)
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2011
2011
Rab GTPases are key regulators of membrane traffic pathways within eukaryotic cells. They are specifically activated by guanine… (More)
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2009
2009
We investigated the physiological role of endogenous MAPK-activating death domain-containing protein (MADD), a splice variant of… (More)
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Highly Cited
2008
Highly Cited
2008
Synaptic proteins are synthesized in the cell body and transported down the axon by microtubule-dependent motors. We previously… (More)
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2006
2006
The IG20 gene is overexpressed in human tumors and cancer cell lines, and encodes at least four splice variants (SVs) namely… (More)
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2004
2004
We identified seven putative splice variants of the human IG20 gene. Four variants namely, IG20, MADD, IG20-SV2 and DENN-SV are… (More)
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2001
2001
We identified a novel cDNA (IG20) that is homologous to cDNAs encoding a protein differentially expressed in normal and… (More)
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