MADD protein

Known as: Insulinoma-Glucagonoma Protein 20, MAP Kinase-Activating Death Domain Protein, MAP-Kinase Activating Death Domain-Containing Protein 
Encoded by MADD Gene, MADD Protein Isoforms A-G are expressed in adult testis, ovary, brain, heart, and fetal brain and kidney. The 1588-amino acid… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2016
02419862016

Papers overview

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2014
2014
Mitogen-activated kinase activating death domain containing protein (MADD) is abundantly expressed in cancer cells and necessary… (More)
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2011
Highly Cited
2011
In tumours, aberrant splicing generates variants that contribute to multiple aspects of tumour establishment, progression and… (More)
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2010
2010
MADD plays an essential role in cancer cell survival. Abrogation of endogenous MADD expression results in significant spontaneous… (More)
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Highly Cited
2008
Highly Cited
2008
Synaptic proteins are synthesized in the cell body and transported down the axon by microtubule-dependent motors. We previously… (More)
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2007
2007
The MADD variant of the IG20 gene is necessary and sufficient for cancer cell survival. Abrogation of MADD, but not the other… (More)
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2005
2005
Rab3A, a member of the Rab3 small GTP-binding protein (G protein) family, regulates Ca(2+)-dependent exocytosis of… (More)
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2001
2001
We identified a novel cDNA (IG20) that is homologous to cDNAs encoding a protein differentially expressed in normal and… (More)
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2000
2000
Death domains (DD) and leucine rich repeats (LRR) are two different types of protein interaction motifs. Death domains are found… (More)
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1999
1999
Engagement of the tumor necrosis factor-alpha (TNF-alpha) receptors by the TNF-alpha ligand results in the rapid induction of TNF… (More)
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1997
1997
The death domain of the type 1 tumor necrosis factor receptor (TNFR1) mediates interactions with several proteins involved in… (More)
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