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Loss of Heterozygosity

Known as: LOH, Allelic Loss, Heterozygosity Loss 
A DNA sequence alteration process in which gain, loss, or exchange of DNA results in loss of function of one allele in a diploid cell. This term is… 
National Institutes of Health

Related topics

Related topics

8 relations

Broader (2)

Gene MutationMutation
HemizygoteLINC00312 geneNeoplastic ProcessesTumor Progression

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Thermo-Moisture Responsive Polyurethane Shape Memory Polymer for Biomedical Devices
Shape memory polymers (SMPs) have a number of advantages as compared with their metal counterpart, i.e., shape memory alloys, in… 
2009
2009
Three-level neutral-point-clamped matrix converter topology
  • M. Lee
  • 2009
  • Corpus ID: 106431913
Matrix converter is a direct AC-AC converter topology that is able to directly convert energy from an AC source to an AC load… 
1998
1998
Vegetable oils in fermentation: beneficial effects of low-level supplementation
To evaluate their potential to enhance fermentation performance, vegetable oils were investigated in a model tetracycline… 
1997
1997
Microsatellite instability and loss of heterozygosity in gastric lymphoma.
To evaluate the significance of microsatellite instability (MI) and loss of heterozygosity (LOH) in the development of gastric… 
1996
1996
Loss of heterozygosity of multiple tumor suppressor genes in human gastric cancers by polymerase chain reaction.
Loss of heterozygosity (LOH) occurring on various chromosomes has been described in the majority of human tumors and its targets… 
Highly Cited
1995
Highly Cited
1995
Identification of multiple breast cancers of multicentric origin by histological observations and distribution of allele loss on chromosome 16q.
Breast cancer is often detected as multiple lesions clinically and/or histopathologically. To examine if the origin of such… 
1985
1985
Analysis of length-of-stay differences between investor-owned and voluntary hospitals.
In contrast to assertions that investor-owned (I-O) hospitals are more efficient than voluntary hospitals, this study finds no… 
Review
1982
Review
1982
Estimation of genetic variability in natural populations of Drosophila simulans by two-dimensional and starch gel electrophoresis.
Genic variation in natural populations of Drosophila simulans was surveyed using allozymic and two-dimensional electrophoretic… 
Review
1980
Review
1980
Lack of genic variation in the abundant proteins of human kidney.
Abundant proteins of 25 human kidneys were surveyed for genic variation by means of two-dimensional electrophoresis. Eighty-three… 
1958
1958
Studies on Periplaneta americana
IN an earlier account we described the occurrence of interchange heterozygosity in a wild isolated population of the American…