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The Apportionment of Human Diversity
It has always been obvious that organisms vary, even to those pre-Darwinian idealists who saw most individual variation as distorted shadows of an ideal. It has been equally apparent, even to thoseExpand
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An Introduction to Genetic Statistics
TLDR
A reviewer for the Journal of the Royal Statistical Society of England comments "This book covering in one volume all important topics in genetical statistics." Written to provide basic probability ideas in terms of genetic situations, since the theory of genetics is a probability theory; to give a definitive treatment of applications of these ideas to genetic theory; and to describe statistical methods appropriate to the data models that are developed. Expand
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The spandrels of San Marco and the Panglossian paradigm: a critique of the adaptationist programme
An adaptationist programme has dominated evolutionary thought in England and the United States during the past 40 years. It is based on faith in the power of natural selection as an optimizing agent.Expand
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The Interaction of Selection and Linkage. I. General Considerations; Heterotic Models.
HILE the theory of the genetic changes in a population due to selection is quite well understood for single loci, our theory for multiple-gene characters is in a rudimentary stage. Most of theExpand
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Distribution of gene frequency as a test of the theory of the selective neutrality of polymorphisms.
The variation in gene frequency among populations or between generations within a population is a result of breeding structure and selection. But breeding structure should affect all loci and allelesExpand
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THE UNITS OF SELECTION
The principle of natural selection as the motive force for evolution was framed by Darwin in terms of a "struggle for existence" on the part of organisms living in a finite and risky environment. TheExpand
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On measures of gametic disequilibrium.
Various measures have been proposed for characterizing the statistical association that arises between alleles at different loci. Hedrick has compared these measures with the standardized measure D'Expand
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PERSPECTIVE:EVOLUTION AND DETECTION OF GENETIC ROBUSTNESS
Abstract Robustness is the invariance of phenotypes in the face of perturbation. The robustness of phenotypes appears at various levels of biological organization, including gene expression, proteinExpand
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On population growth in a randomly varying environment.
  • R. Lewontin, D. Cohen
  • Mathematics, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1 April 1969
If a population is growing in a randomly varying environment, such that the finite rate of increase per generation is a random variable with no serial autocorrelation, the logarithm of populationExpand
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A molecular approach to the study of genic heterozygosity in natural populations. II. Amount of variation and degree of heterozygosity in natural populations of Drosophila pseudoobscura.
S pointed out in the first paper of this series (HUBBY and LEWONTIN 1966), A no one knows at the present time the kinds and frequencies of variant alleles present in natural populations of anyExpand
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