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Long-Term Potentiation

Known as: long-term potentiation (LTP), long-term synaptic potentiation, Long Term Potentiation 
A persistent increase in synaptic efficacy, usually induced by appropriate activation of the same synapses. The phenomenological properties of long… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

Membrane PotentialsNeuronal Plasticity
aspects of radiation effectsphysiological aspects

Papers overview

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Highly Cited
2007
Highly Cited
2007
Opioids block long-term potentiation of inhibitory synapses
Excitatory brain synapses are strengthened or weakened in response to specific patterns of synaptic activation, and these changes… 
Highly Cited
2003
Highly Cited
2003
Perceptual Correlates of Nociceptive Long-term Potentiation and Long-term Depression in Humans
Long-term potentiation (LTP) and long-term depression (LTD) of synaptic strength are ubiquitous mechanisms of synaptic plasticity… 
Highly Cited
2002
Highly Cited
2002
Postsynaptic Induction of BDNF-Mediated Long-Term Potentiation
Brain-derived neurotrophic factor (BDNF) and other neurotrophins are critically involved in long-term potentiation (LTP… 
Highly Cited
2000
Highly Cited
2000
Dopamine and cAMP-Regulated Phosphoprotein 32 kDa Controls Both Striatal Long-Term Depression and Long-Term Potentiation, Opposing Forms of Synaptic Plasticity
A complex chain of intracellular signaling events, critically important in motor control, is activated by the stimulation of D1… 
Highly Cited
1997
Highly Cited
1997
Mice Lacking Metabotropic Glutamate Receptor 5 Show Impaired Learning and Reduced CA1 Long-Term Potentiation (LTP) But Normal CA3 LTP
Class I metabotropic glutamate receptors (mGluRs) have been postulated to play a role in synaptic plasticity. To test the… 
Highly Cited
1994
Highly Cited
1994
Hippocampal long-term potentiation and neural cell adhesion molecules L1 and NCAM
SYNAPTIC membranes express cell adhesion molecules1. Here we investigate the role of the neural cell adhesion molecules L1 and… 
Highly Cited
1993
Highly Cited
1993
An essential role for protein phosphatases in hippocampal long-term depression.
The effectiveness of long-term potentiation (LTP) as a mechanism for information storage would be severely limited if processes… 
Highly Cited
1992
Highly Cited
1992
Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice.
As a first step in a program to use genetically altered mice in the study of memory mechanisms, mutant mice were produced that do… 
Highly Cited
1990
Highly Cited
1990
Two components of long-term potentiation induced by different patterns of afferent activation
LONG-TERM potentiation (LTP) of excitatory synaptic transmission1–4 could be a mechanism underlying memory3,5. Induction of LTP… 
Highly Cited
1990
Highly Cited
1990
Presynaptic mechanism for long-term potentiation in the hippocampus
Experiments analysing the statistical properties of synaptic transmission, before and after the induction of long-term… 
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