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Levorphanol
Known as:
Levorphan
, Levodroman
, Morphinan-3-ol, 17-methyl-
Â
(More)
A synthetic derivative of morphine with analgesic activities. Levorphanol mimics the actions of morphine, however, it is about 8 times more potent…Â
(More)
National Institutes of Health
Topic mentions per year
Topic mentions per year
1953-2018
0
10
20
30
1953
2017
Related topics
Related topics
20 relations
Broader (5)
Analgesics, Opioid
Morphinans
Narcotic Analgesics
Narcotics
(More)
Drug Allergy
In Blood
Opioid Agonists [MoA]
Pain
(More)
Narrower (1)
Levorphanol Tartrate
Related mentions per year
Related mentions per year
1936-2018
1940
1960
1980
2000
2020
Levorphanol
Pain
Drug Allergy
agonists
Pregnancy
Narcotics
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Oral opioid therapy for chronic peripheral and central neuropathic pain.
Michael C. Rowbotham
,
Lisa Twilling
,
Pamela Stitzlein Davies
,
Lori Reisner
,
Kirk Taylor
,
David C Mohr
The New England journal of medicine
2003
BACKGROUND Although opioids are commonly used to treat chronic neuropathic pain, there are limited data to guide their use. Few…Â
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1992
1992
Kappa 3 receptors and levorphanol-induced analgesia.
Leslie A Tive
,
K B Ginsberg
,
Chaim Gideon Pick
,
Grzegorz Pasternak
Neuropharmacology
1992
Levorphanol is a widely used opiate analgesic. Although structurally related to morphine, levorphanol has high affinity for a…Â
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Highly Cited
1992
Highly Cited
1992
The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization.
Brigitte Lina Kieffer
,
Katia Befort
,
Claire Gavériaux-Ruff
,
Christine Hirth
Proceedings of the National Academy of Sciences…
1992
A random primed expression cDNA library was constructed from the RNA of NG 108-15 cells. Pools of plasmid DNA were transfected…Â
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1988
1988
Unidirectional analgesic cross-tolerance between morphine and levorphanol in the rat.
David Moulin
,
Guanghui Ling
,
Grzegorz Pasternak
Pain
1988
Clinically, patients often demonstrate incomplete cross-tolerance between opiate analgesics. Although dispositional and…Â
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1988
1988
Effects of levorphanol and several kappa-selective opioids on respiration and behavior in rhesus monkeys.
L. L. Howell
,
Jesús López Bergman
,
W. H. Morse
The Journal of pharmacology and experimental…
1988
The effects of the mu-selective opioid, levorphanol (0.03-1.0 mg/kg), and the kappa-selective opioids, U-50,488 (0.03-1.0 mg/kg…Â
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1987
1987
Dextrorphan and levorphanol selectively block N-methyl-D-aspartate receptor-mediated neurotoxicity on cortical neurons.
D. W. Choi
,
S. Peters
,
V Viseskul
The Journal of pharmacology and experimental…
1987
Neocortical neurons in cell cultures prepared from fetal mice were impaled for intracellular recording. Dextrorphan (DX), a…Â
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1985
1985
Differential effects of dextrorphan and levorphanol on the excitation of rat spinal neurons by amino acids.
Jordan Church
,
David M. Lodge
,
Stewart Berry
European journal of pharmacology
1985
The effects of the stereoisomers dextrorphan and levorphanol on the excitation of spinal neurons by electrophoretically…Â
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1984
1984
Effects of butorphanol, flunixin, levorphanol, morphine, and xylazine in ponies.
Marissak Kalpravidh
,
William V. Lumb
,
M. Wright
,
Richard B. Heath
American journal of veterinary research
1984
The analgesic and behavioral effects of butorphanol (0.22 mg/kg), flunixin (2.2 mg/kg), levorphanol (0.033 mg/kg), morphine (0.66…Â
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Highly Cited
1982
Highly Cited
1982
Drug reinforcement studied by the use of place conditioning in rat.
Ronald F. Mucha
,
Derek van der Kooy
,
Matthew J O'shaughnessy
,
P Bucenieks
Brain research
1982
Rats display a preference for an environment in which they previously received morphine. The present report provides behavioral…Â
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1971
1971
Stereospecific and nonspecific interactions of the morphine congener levorphanol in subcellular fractions of mouse brain.
A. Goldstein
,
Louise Lowney
,
B. K. Pal
Proceedings of the National Academy of Sciences…
1971
A METHOD IS DESCRIBED FOR ANALYZING THE ASSOCIATION OF THE OPIATE NARCOTIC LEVORPHANOL WITH BRAIN TISSUE INTO THREE COMPONENTS…Â
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