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Morphinans

Known as: Morphinans [Chemical/Ingredient], morphinan 
Compounds based on a partially saturated iminoethanophenanthrene, which can be described as ethylimino-bridged benzo-decahydronaphthalenes. They… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Classical opioid analgesics, including morphine, mediate all of their desired and undesired effects by specific activation of the… Expand
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2018
2018
Morphinan-based painkillers are derived from opium poppy (Papaver somniferum L.). We report a draft of the opium poppy genome… Expand
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Highly Cited
2015
Highly Cited
2015
Activation of the μ-opioid receptor (μOR) is responsible for the efficacy of the most effective analgesics. To shed light on the… Expand
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2015
2015
Morphinan alkaloids from the opium poppy are used for pain relief. The direction of metabolites to morphinan biosynthesis… Expand
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Highly Cited
2012
Highly Cited
2012
Opium is one of the world’s oldest drugs, and its derivatives morphine and codeine are among the most used clinical drugs to… Expand
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Highly Cited
2008
Highly Cited
2008
The benzylisoquinoline alkaloids (BIAs) are a diverse class of metabolites that exhibit a broad range of pharmacological… Expand
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Highly Cited
2007
Highly Cited
2007
BackgroundThe mechanisms involved in the induction and regulation of inflammation resulting in dopaminergic (DA) neurotoxicity in… Expand
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Highly Cited
2006
Highly Cited
2006
Male rats are more sensitive to the antinociceptive effects of morphine than female rats. This difference is seen across several… Expand
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2003
2003
In this study positive ESI tandem mass spectra of the [M+H]+ ions of morphinan alkaloids obtained using an ion trap MS were… Expand
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Highly Cited
1998
Highly Cited
1998
UGT2B7 has been cloned and expressed previously in COS cells and HK293 cells. Two forms have been identified: one with a tyrosine… Expand
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