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Levallorphan

Known as: Lévallorphane, Levallorphanum, Levallorphan [Chemical/Ingredient] 
An opioid antagonist with properties similar to those of NALOXONE; in addition it also possesses some agonist properties. It should be used… Expand
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
The rat μ-opioid receptor clone in which novel exon 5 was found in the place of exon 4 (MOR-1B) was one of the first MOR-1… Expand
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Highly Cited
2004
Highly Cited
2004
In rats implanted subcutaneously with morphine containing pellets different degrees of dependence were induced by varying the… Expand
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Highly Cited
1999
Highly Cited
1999
We have identified four new mu-opiod receptor (MOR)-1 exons, indicating that the gene now contains at least nine exons spanning… Expand
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Highly Cited
1999
Highly Cited
1999
The ability of antipsychotic drugs to inhibit the catalytic activity of five cytochrome P-450 (CYP) isoforms was compared using… Expand
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Highly Cited
1997
Highly Cited
1997
G protein activation by different mu-selective opioid agonists was examined in rat thalamus, SK-N-SH cells, and mu-opioid… Expand
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Highly Cited
1995
Highly Cited
1995
The ability of mu-opioid agonists to activate G proteins has been demonstrated by studying the binding of the GTP analogue… Expand
Highly Cited
1980
Highly Cited
1980
The respiratory depressant capacities of intravenous nalbuphine, a potent analgesic of the narcotic antagonist type, and of… Expand
Highly Cited
1977
Highly Cited
1977
The vast majority of morphine-sensitive single units in the area examined were localized to the locus coeruleus. This corresponds… Expand
Highly Cited
1975
Highly Cited
1975
The analgesic activity of morphine and the narcotic antagonists, pentazocine, cyclazocine, levallorphan and nalorphine, was… Expand
Highly Cited
1975
Highly Cited
1975
1 Morphine inhibits the electrically evoked (0.1‐0.15 Hz, 1 ms) contractions of the longitudinal muscle of the mouse vas deferens… Expand