dextrallorphan

We have previously shown that sigma-2 receptors are relatively difficult to solubilize (Eur. J. Pharmacol. 304 (1996) 201… (More)

A simple, achiral monoamine sigma-1 (sigma1) receptor selective ligand (sigma2Ki/sigma1Ki>2000) is described, which could replace… (More)

Sigma receptors are known to be expressed in a variety of human tumor cells, including breast, neural, and melanoma tumors. A… (More)

Thirteen tumor-derived cell lines of human and nonhuman origin and from various tissues were examined for the presence and… (More)

Rat liver and kidney were investigated for the presence of sigma (sigma) receptor subtypes by radioligand binding with three… (More)

2-, 3-, and 4-idophenyl derivatives of the high-affinity sigma ligand N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1-pyrrolidinyl… (More)

Iontophoretic application of the sigma ligands, 1,3-di-o-tolylguanidine (DTG), dextrallorphan, and (+)-pentazocine reliably… (More)

Two highly selective radiolabeled probes for sigma receptors were found to bind with high affinity and capacity to membranes from… (More)

The calcium binding protein calmodulin and the opiate receptor binding sites are unevenly distributed in various subcellular… (More)

A portion of the specific binding of tritiated SKF-10047 to the guinea-pig brain suspension of the particulate fraction is not… (More)