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LTK protein, human

Known as: Protein Tyrosine Kinase 1, leukocyte tyrosine kinase protein, human, Protein Tyrosine Kinase-1 
Leukocyte tyrosine kinase receptor (864 aa, ~92 kDa) is encoded by the human LTK gene. This protein plays a role in tyrosine phosphorylation… 
National Institutes of Health

Related topics

Related topics

22 relations
Cell Differentiation processCell ProliferationEnzyme GeneEphrin Receptor EphA8

Broader (2)

Protein Tyrosine KinaseReceptor Protein-Tyrosine Kinases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Apoptosis-associated tyrosine kinase 1 inhibits growth and migration and promotes apoptosis in melanoma
Apoptosis-associated tyrosine kinase 1 (AATK1) was initially identified as a protein that was dramatically overexpressed during… 
Highly Cited
2014
Highly Cited
2014
Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome
Significance Secreted factors and their cell-surface receptors play important roles in the communication between cells in normal… 
Review
2013
Review
2013
Anaplastic lymphoma kinase (ALK): structure, oncogenic activation, and pharmacological inhibition.
2009
2009
Cytoplasmic ACK1 Interaction with Multiple Receptor Tyrosine Kinases Is Mediated by Grb2
ACK1 (activated Cdc42-associated kinase 1), a cytoplsmic tyrosine kinase, is implicated in metastatic behavior, cell spreading… 
Highly Cited
2006
Highly Cited
2006
Phase II study of lapatinib, a dual inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase 1 and 2 (Her2/Neu) in patients (pts) with advanced biliary tree cancer (BTC) or hepatocellular…
4010 Background: Advanced BTC (gallbladder, bile duct) and HCC respond poorly to systemic chemotherapy. Lapatinib is an oral… 
Highly Cited
2005
Highly Cited
2005
Identification of metastasis-associated receptor tyrosine kinases in non-small cell lung cancer.
Development of distant metastasis after tumor resection is the leading cause of death in early-stage non-small cell lung cancer… 
Highly Cited
2004
Highly Cited
2004
High-Throughput Analysis of Genome-Wide Receptor Tyrosine Kinase Expression in Human Cancers Identifies Potential Novel Drug Targets
Novel high-throughput analyses in molecular biology allow sensitive and rapid identification of disease-related genes and drug… 
1997
1997
The phosphatidylinositol 3′ kinase pathway is required for the survival signal of leukocyte tyrosine kinase
Leukocyte tyrosine kinase (LTK) is a receptor tyrosine kinase which belongs to the insulin receptor superfamily and is mainly… 
1996
1996
Growth and Survival Signals transmitted via Two Distinct NPXY Motifs within Leukocyte Tyrosine Kinase, an Insulin Receptor-related Tyrosine Kinase*
Leukocyte tyrosine kinase (LTK) is a receptor tyrosine kinase, which belongs to the insulin receptor family and is mainly… 
1993
1993
Differently spliced cDNAs of human leukocyte tyrosine kinase receptor tyrosine kinase predict receptor proteins with and without a tyrosine kinase domain and a soluble receptor protein.
Leukocyte tyrosine kinase (LTK) is a tyrosine kinase that has been suggested to be specific for hematopoietic cells and neuronal… 
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