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Protein Tyrosine Kinase

Known as: Tyrosine Protein Kinases, Tyrosine-Specific Protein Kinases, Tyrosylprotein Kinase 
Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling, and can be divided into two subfamilies… Expand
National Institutes of Health

Related topics

Related topics

49 relations

Narrower (31)

Bmx protein, mouseBmx protein, ratEPHA4 protein, humanEphrin Receptor EphB1
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Cell Differentiation processCell ProliferationEnzyme GeneExtracellular Signal Regulated Kinases
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Targeting FLT3 mutations in AML: review of current knowledge and evidence
Genomic investigations of acute myeloid leukemia (AML) have demonstrated that several genes are recurrently mutated, leading to… Expand
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Review
2019
Review
2019
The molecular machinery of regulated cell death
Cells may die from accidental cell death (ACD) or regulated cell death (RCD). ACD is a biologically uncontrolled process, whereas… Expand
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Review
2019
Review
2019
Cellular signalling by primary cilia in development, organ function and disease
Primary cilia project in a single copy from the surface of most vertebrate cell types; they detect and transmit extracellular… Expand
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Review
2019
Review
2019
Perioperative opioid analgesia—when is enough too much? A review of opioid-induced tolerance and hyperalgesia
Opioids are a mainstay of acute pain management but can have many adverse effects, contributing to problematic long-term use… Expand
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Review
2019
Review
2019
Towards individualized therapy for metastatic renal cell carcinoma
Over the past decade, the treatment landscape for patients with metastatic renal cell carcinoma (RCC) has evolved dramatically… Expand
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Review
2019
Review
2019
Recent advances on anti-angiogenesis receptor tyrosine kinase inhibitors in cancer therapy
Angiogenesis has always been the topic of major scientific interest in the field of malignant tumors. Nowadays, targeting… Expand
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Review
2018
Review
2018
Immunological and toxicological risk assessment of e-cigarettes
Knowledge of the long-term toxicological and immunological effects of e-cigarette (e-cig) aerosols remains elusive due to the… Expand
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Review
2017
Review
2017
FGFR-TACC gene fusions in human glioma
Chromosomal translocations joining in-frame members of the fibroblast growth factor receptor-transforming acidic coiled-coil gene… Expand
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Highly Cited
2004
Highly Cited
2004
EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy
Receptor tyrosine kinase genes were sequenced in non–small cell lung cancer (NSCLC) and matched normal tissue. Somatic mutations… Expand
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Review
1995
Review
1995
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
A number of different intracellular signaling pathways have been shown to be activated by receptor tyrosine kinases. These… Expand
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