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Protein Tyrosine Kinase

Known as: Tyrosine Protein Kinases, Tyrosine-Specific Protein Kinases, Tyrosylprotein Kinase 
Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling, and can be divided into two subfamilies… 
National Institutes of Health

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Narrower (31)

Bmx protein, mouseBmx protein, ratEPHA4 protein, humanEphrin Receptor EphB1
Cell Differentiation processCell ProliferationEnzyme GeneExtracellular Signal Regulated Kinases

Papers overview

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Highly Cited
2005
Highly Cited
2005
Molecular characterization of the idiopathic hypereosinophilic syndrome (HES) in 35 French patients with normal conventional cytogenetics
Idiopathic hypereosinophilic syndrome (HES) characterized by unexplained and persistent hypereosinophilia is heterogeneous and… 
Highly Cited
1998
Highly Cited
1998
Tyrosine 112 of Latent Membrane Protein 2A Is Essential for Protein Tyrosine Kinase Loading and Regulation of Epstein-Barr Virus Latency
ABSTRACT Latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV) is expressed on the plasma membrane of B lymphocytes… 
Highly Cited
1996
Highly Cited
1996
Mocarhagin, a novel cobra venom metalloproteinase, cleaves the platelet von Willebrand factor receptor glycoprotein Ibalpha. Identification of the sulfated tyrosine/anionic sequence Tyr-276-Glu-282…
Platelet adhesion to the subendothelium is the initiating event in hemostasis and thrombosis and involves the binding of von… 
Highly Cited
1995
Highly Cited
1995
Activation of Tsk and Btk tyrosine kinases by G protein beta gamma subunits.
Tsk/Itk and Btk are members of the pleckstrin-homology (PH) domain-containing tyrosine kinase family. The PH domain has been… 
Highly Cited
1994
Highly Cited
1994
Mutagenic analysis of the roles of SH2 and SH3 domains in regulation of the Abl tyrosine kinase
We have used in vitro mutagenesis to examine in detail the roles of two modular protein domains, SH2 and SH3, in the regulation… 
Highly Cited
1991
Highly Cited
1991
A specific type of ganglioside as a modulator of insulin-dependent cell growth and insulin receptor tyrosine kinase activity. Possible association of ganglioside-induced inhibition of insulin…
Insulin-dependent cell growth has been correlated with insulin receptor function, particularly receptor-associated kinase… 
Review
1991
Review
1991
Signal transduction and the fate of the R7 photoreceptor in Drosophila.
Highly Cited
1990
Highly Cited
1990
CD45, an integral membrane protein tyrosine phosphatase. Characterization of enzyme activity.
Highly Cited
1989
Highly Cited
1989
Epidermal growth factor stimulates tyrosine phosphorylation of phospholipase C-II independently of receptor internalization and extracellular calcium.
Epidermal growth factor (EGF) rapidly stimulates the formation of inositol 1,4,5-trisphosphate in a variety of cell types… 
Highly Cited
1984
Highly Cited
1984
Nucleotide sequence of the feline retroviral oncogene v-fms shows unexpected homology with oncogenes encoding tyrosine-specific protein kinases.
The nucleotide sequence encoding the transforming polyprotein of the McDonough strain of feline sarcoma virus was determined… 
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