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Protein Tyrosine Kinase

Known as: Tyrosine Protein Kinases, Tyrosine-Specific Protein Kinases, Tyrosylprotein Kinase 
Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling, and can be divided into two subfamilies… 
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Signaling through the Ror2 receptor tyrosine kinase promotes invadopodia formation for tumor invasion. Here, we identify… 
Highly Cited
2004
Highly Cited
2004
Receptor tyrosine kinase genes were sequenced in non–small cell lung cancer (NSCLC) and matched normal tissue. Somatic mutations… 
Highly Cited
2004
Highly Cited
2004
BACKGROUND Most patients with non-small-cell lung cancer have no response to the tyrosine kinase inhibitor gefitinib, which… 
Review
2001
Review
2001
Protein-tyrosine kinases (PTKs) are important regulators of intracellular signal-transduction pathways mediating development and… 
Highly Cited
2000
Highly Cited
2000
The inadvertent activation of the Abelson tyrosine kinase (Abl) causes chronic myelogenous leukemia (CML). A small-molecule… 
Highly Cited
1996
Highly Cited
1996
The bcr–abl oncogene, present in 95% of patients with chronic myelogenous leukemia (CML), has been implicated as the cause of… 
Review
1995
Review
1995
The eukaryotic protein kinases make up a large superfamily of homologous proteins. They are related by virtue of their kinase… 
Review
1995
Review
1995
  • A. Newton
  • Journal of Biological Chemistry
  • 1995
  • Corpus ID: 28248489
The protein kinase C family of enzymes transduces the myriad of signals promoting lipid hydrolysis. The prevalence of this enzyme… 
Highly Cited
1993
Highly Cited
1993
The epidermal growth factor receptor (EGFR) is one member of the ERBB family of transmembrane gly-coprotein tyrosine receptor…