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Protein Tyrosine Kinase

Known as: Tyrosine Protein Kinases, Tyrosine-Specific Protein Kinases, Tyrosylprotein Kinase 
Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling, and can be divided into two subfamilies… 
National Institutes of Health

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Narrower (31)

Bmx protein, mouseBmx protein, ratEPHA4 protein, humanEphrin Receptor EphB1
Cell Differentiation processCell ProliferationEnzyme GeneExtracellular Signal Regulated Kinases

Papers overview

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Highly Cited
2007
Highly Cited
2007
Predictive Value of Maternal Angiogenic Factors in Second Trimester Pregnancies With Abnormal Uterine Perfusion
Angiogenic factors like placental growth factor and its antiangiogenic antagonist soluble fms-like tyrosine kinase 1 (sFlt1) are… 
Highly Cited
1996
Highly Cited
1996
Daughter of Sevenless Is a Substrate of the Phosphotyrosine Phosphatase Corkscrew and Functions during Sevenless Signaling
Highly Cited
1994
Highly Cited
1994
Signals determining protein tyrosine kinase and glycosyl-phosphatidylinositol-anchored protein targeting to a glycolipid-enriched membrane fraction
Glycosyl-phosphatidylinositol (GPI)-anchored membrane proteins and certain protein tyrosine kinases associate with a Triton X-100… 
Highly Cited
1994
Highly Cited
1994
Binding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase.
Bruton tyrosine kinase (Btk) has been implicated as the defective gene in both human and murine B-cell deficiencies. The… 
Highly Cited
1989
Highly Cited
1989
Direct activation of the serine/threonine kinase activity of raf-1 through tyrosine phosphorylation by the PDGF β-receptor
Highly Cited
1989
Highly Cited
1989
Epidermal growth factor stimulates tyrosine phosphorylation of phospholipase C-II independently of receptor internalization and extracellular calcium.
Epidermal growth factor (EGF) rapidly stimulates the formation of inositol 1,4,5-trisphosphate in a variety of cell types… 
Highly Cited
1989
Highly Cited
1989
T cell activation induces rapid tyrosine phosphorylation of a limited number of cellular substrates.
Highly Cited
1988
Highly Cited
1988
Identification of multiple novel polypeptide substrates of the v-src, v-yes, v-fps, v-ros, and v-erb-B oncogenic tyrosine protein kinases utilizing antisera against phosphotyrosine.
Antibodies to phosphotyrosine were used to identify proteins phosphorylated on tyrosine in chicken embryo fibroblasts transformed… 
Highly Cited
1988
Highly Cited
1988
Antiphosphotyrosine recovery of phospholipase C activity after EGF treatment of A-431 cells.
A tenfold increase in phospholipase C activity specific for phosphatidylinositol 4,5-bisphosphate (PIP2) was immunopurified from… 
Highly Cited
1985
Highly Cited
1985
Antibodies against a synthetic peptide as a probe for the kinase activity of the avian EGF receptor and v-erbb protein
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