Protein Tyrosine Kinase

Known as: Tyrosine Protein Kinases, Tyrosine-Specific Protein Kinases, Tyrosylprotein Kinase 
Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling, and can be divided into two subfamilies… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Anaplastic thyroid carcinoma (ATC) is a rare malignancy, accounting for 1–2% of all thyroid cancers. Although rare, ATC accounts… (More)
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Review
2017
Review
2017
Cadherins are homophilic adhesion molecules with important functions in cell-cell adhesion, tissue morphogenesis, and cancer. In… (More)
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Review
2017
Review
2017
The fibroblast growth factor/fibroblast growth factor receptor (FGF/FGFR) is a tyrosine kinase signaling pathway that has a… (More)
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Review
2017
Review
2017
Rituximab is a chimeric mouse/human anti-CD20 monoclonal immunoglobulin. We reviewed the efficacy and safety of rituximab in 169… (More)
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Review
2017
Review
2017
The anaplastic lymphoma kinase (ALK) gene plays an important physiologic role in the development of the brain and can be… (More)
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Review
2017
Review
2017
Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family of secreted proteins. Signaling cascades induced… (More)
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Highly Cited
2006
Highly Cited
2006
Stimulation of the insulin and insulin-like growth factor I (IGF-I) receptor activates the phosphoinositide-3-kinase/Akt/mTOR… (More)
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Highly Cited
2003
Highly Cited
2003
Preeclampsia, a syndrome affecting 5% of pregnancies, causes substantial maternal and fetal morbidity and mortality. The… (More)
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Highly Cited
2000
Highly Cited
2000
Human breast tumours are diverse in their natural history and in their responsiveness to treatments. Variation in transcriptional… (More)
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Highly Cited
1996
Highly Cited
1996
The bcr–abl oncogene, present in 95% of patients with chronic myelogenous leukemia (CML), has been implicated as the cause of… (More)
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