LIMK1 protein, human

Known as: LIM Domain Kinase 1, LIMK-1 protein, LIM KINASE 
LIM domain kinase 1 (647 aa, ~73 kDa) is encoded by the human LIMK1 gene. This protein is involved in both actin cytoskeleton organization and serine… (More)
National Institutes of Health

Papers overview

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2010
2010
Overexpression, genetic amplification and mutations of p21-activated kinase 4 (PAK4) were found in a variety of human cancers… (More)
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2009
2009
Proper regulation of the cAMP-dependent protein kinase (protein kinase A, PKA) is necessary for cellular homeostasis, and… (More)
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Highly Cited
2008
Highly Cited
2008
Hepatocyte growth factor (HGF) is associated with tumour progression and increases the invasiveness of prostate carcinoma cells… (More)
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Highly Cited
2006
Highly Cited
2006
Understanding the mechanisms controlling cancer cell invasion and metastasis constitutes a fundamental step in setting new… (More)
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Highly Cited
2004
Highly Cited
2004
The growth and morphological differentiation of dendrites are critical events in the establishment of proper neuronal… (More)
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Highly Cited
2004
Highly Cited
2004
LATS (large tumour suppressor) is a family of conserved tumour suppressors identified in Drosophila and mammals. Here we show… (More)
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Highly Cited
2004
Highly Cited
2004
In this study, we examined the subcellular distribution and functions of LIMK1 in developing neurons. Confocal microscopy… (More)
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Highly Cited
2001
Highly Cited
2001
LIM-kinase 1 (LIMK1) and LIM-kinase 2 (LIMK2) regulate actin cytoskeletal reorganization via cofilin phosphorylation downstream… (More)
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Highly Cited
2001
Highly Cited
2001
LIM-kinase 1 and 2 (LIMK1 and LIMK2) phosphorylate cofilin and induce actin cytoskeletal reorganization. LIMK1 is activated by… (More)
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Highly Cited
2000
Highly Cited
2000
LIM-kinase 1 (LIMK1) phosphorylates cofilin, an actin-depolymerizing factor, and regulates actin cytoskeletal reorganization… (More)
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