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L 745870

Known as: L 745,870, L745,870, L745870 
National Institutes of Health

Papers overview

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2010
2010
Validation and pharmacological characterisation of MK-801-induced locomotor hyperactivity in BALB/C mice as an assay for detection of novel antipsychotics
RationaleWe evaluated locomotor hyperactivity induced in BALB/C mice by an N-methyl-d-aspartate receptor antagonist MK-801 as an… 
2009
2009
Dopamine receptor subtypes contribution to Homer1a induction: Insights into antipsychotic molecular action
Highly Cited
2007
Highly Cited
2007
F15063, a compound with D2/D3 antagonist, 5‐HT1A agonist and D4 partial agonist properties: (III) Activity in models of cognition and negative symptoms
The D2/D3 receptor antagonist, D4 receptor partial agonist, and high efficacy 5‐HT1A receptor agonist F15063 was shown to be… 
2004
2004
Comparative pharmacology of human dopamine D(2)-like receptor stable cell lines coupled to calcium flux through Galpha(qo5).
Highly Cited
2003
Highly Cited
2003
Facilitatory effect of the dopamine D4 receptor agonist PD168,077 on memory consolidation of an inhibitory avoidance learned response in C57BL/6J mice
2003
2003
Dopamine D4 receptor-mediated presynaptic inhibition of GABAergic transmission in the rat supraoptic nucleus.
The mechanism by which dopamine induces or facilitates neurohypophysial hormone release is not completely understood. Because… 
Highly Cited
2000
Highly Cited
2000
Dopamine D1 Receptors Synergize with D2, But Not D3 or D4, Receptors in the Striatum without the Involvement of Action Potentials
The widespread biological actions of the neurotransmitter dopamine (DA) are mediated by two classes of receptor, the D1 class (D1… 
1999
1999
S-16924, a novel, potential antipsychotic with marked serotonin1A agonist properties. IV. A drug discrimination comparison with clozapine.
The novel benzodioxopyrrolidine (S-16924) displays a clozapine-like profile of interaction with multiple monoaminergic receptors… 
Highly Cited
1998
Highly Cited
1998
Discriminative stimulus properties of the atypical neuroleptic clozapine in rats: tests with subtype selective receptor ligands
The interoceptive stimulus induced by clozapine (5 mg/kg, i.p.) has been characterized in an operant drug discrimination… 
Highly Cited
1997
Highly Cited
1997
Regional distribution of dopamine D4 receptors in rat forebrain
BINDING of the D2-like (D2/D3/D4) radioligand [3H]nemonapride under selective conditions (with 300 nM S[−]-raclopride and other… 
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