• Publications
  • Influence
The induction of pain: an integrative review
  • M. Millan
  • Biology
    Progress in Neurobiology
  • 31 January 1999
The neurobiology and control of anxious states
  • M. Millan
  • Biology, Psychology
    Progress in Neurobiology
  • 1 June 2003
Descending control of pain
  • M. Millan
  • Biology
    Progress in Neurobiology
  • 1 April 2002
The Novel Melatonin Agonist Agomelatine (S20098) Is an Antagonist at 5-Hydroxytryptamine2C Receptors, Blockade of Which Enhances the Activity of Frontocortical Dopaminergic and Adrenergic Pathways
TLDR
In contrast to melatonin, agomelatine behaves as an antagonist at 5- HT2B and 5-HT2C receptors: blockade of the latter reinforces frontocortical adrenergic and dopaminergic transmission.
Serotonin2C receptors tonically suppress the activity of mesocortical dopaminergic and adrenergic, but not serotonergic, pathways: A combined dialysis and electrophysiological analysis in the rat
TLDR
5‐HT2C receptors exert a tonic, suppressive influence on the activity of mesocortical — as well as mesolimbic and nigrostriatal — dopaminergic pathways, likely via indirect actions expressed at the level of their cell bodies.
Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy
TLDR
This article critically discusses the challenges and opportunities for improving cognition in individuals suffering from psychiatric disorders, highlighting the needs to characterize the cellular and cerebral circuits underpinning cognitive function and identify more effective treatments.
Differential Actions of Antiparkinson Agents at Multiple Classes of Monoaminergic Receptor. I. A Multivariate Analysis of the Binding Profiles of 14 Drugs at 21 Native and Cloned Human Receptor
TLDR
An innovative multivariate analysis revealed marked heterogeneity in binding profiles of antiparkinson agents at diverse receptors implicated in the etiology and/or treatment of Parkinson's disease.
(1-(2,5-dimethoxy-4 iodophenyl)-2-aminopropane)-induced head-twitches in the rat are mediated by 5-hydroxytryptamine (5-HT) 2A receptors: modulation by novel 5-HT2A/2C antagonists, D1 antagonists and
TLDR
It is demonstrated that 5-HT2A receptors mediate HTW in rats and that both D1 and D2 receptors as well as (postsynaptic) 5- HT1A receptors play a role in their expression.
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