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Ku70 protein

Known as: X ray Repair Cross Complementing Protein 6, X-ray Repair Cross-Complementing Protein 6, Ku70 
X-ray repair cross-complementing protein 6 (609 aa, ~70 kDa) is encoded by the human XRCC6 gene. This protein plays a role in DNA non-homologous end… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
The dynamic and multicellular processes of neuroinflammation are mediated by the nonneuronal cells of the central nervous system… Expand
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Highly Cited
2014
Highly Cited
2014
Comprehensive analyses of cancer genomes promise to inform prognoses and precise cancer treatments. A major barrier, however, is… Expand
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Highly Cited
2014
Highly Cited
2014
The ability to isolate and analyze rare circulating tumor cells (CTCs) has the potential to further our understanding of cancer… Expand
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Highly Cited
2007
Highly Cited
2007
Viable tumour-derived epithelial cells (circulating tumour cells or CTCs) have been identified in peripheral blood from cancer… Expand
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Highly Cited
2006
Highly Cited
2006
DNA double-strand break (DSB) repair by nonhomologous end joining (NHEJ) requires the assembly of several proteins on DNA ends… Expand
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Highly Cited
2004
Highly Cited
2004
Apoptosis is a key tumor suppression mechanism that can be initiated by activation of the proapoptotic factor Bax. The Ku70 DNA… Expand
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Highly Cited
2003
Highly Cited
2003
Bax induces mitochondrial-dependent cell death signals in mammalian cells. However, the mechanism of how Bax is kept inactive has… Expand
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Highly Cited
1997
Highly Cited
1997
V(D)J recombination requires both lymphoid-specific and generally expressed enzymatic activities. All three known generally… Expand
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Highly Cited
1992
Highly Cited
1992
The redox dye 5-cyano-2,3-ditolyl tetrazolium chloride (CTC) was employed for direct epifluorescent microscopic enumeration of… Expand
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Highly Cited
1992
Highly Cited
1992
  • J. S. Lai, W. Herr
  • Proceedings of the National Academy of Sciences…
  • 1992
  • Corpus ID: 9500856
DNA-dependent and DNA-independent associations of DNA-binding proteins are important in transcriptional regulation. The analysis… Expand
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