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G22P1 wt Allele

Known as: Thyroid Autoantigen 70kD (Ku Antigen) Gene, Ku70, G22P1 
Human XRCC6 wild-type allele is located within 22q13.2-q13.31 and is approximately 43 kb in length. This allele, which encodes X-ray repair cross… 
National Institutes of Health

Related topics

Related topics

10 relations
DNA RepairHomo sapiensKu70 proteinLupus Erythematosus, Systemic

Papers overview

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Review
2009
Review
2009
DeubiKuitylation: A novel DUB enzymatic activity for the DNA repair protein, Ku70
The Ku70 protein was shown to be involved in multiple cellular pathways including DNA repair, telomere maintenance, V(D)J… 
2007
2007
Transient depletion of Ku70 and Xrcc4 by RNAi as a means to manipulate the non-homologous end-joining pathway.
Highly Cited
2005
Highly Cited
2005
Ku protein targeting by Ku70 small interfering RNA enhances human cancer cell response to topoisomerase II inhibitor and γ radiation
Ku protein is a heterodimer (Ku70 and Ku86) known to play an important role in V(D)J recombination, apoptosis, telomere fusion… 
2003
2003
Prediction of tumor radiosensitivity in rectal carcinoma based on p53 and Ku70 expression.
The identification of predictive indicators of radiosensitivity is extremely useful in selecting patients suited for preoperative… 
Highly Cited
2001
Highly Cited
2001
Decreased expression of DNA-dependent protein kinase, a DNA repair protein, during human colon carcinogenesis.
DNA-dependent protein kinase (DNA-PK), consisting of a catalytic subunit (DNA-PKcs) and the Ku70 and Ku86 proteins, participates… 
1996
1996
Expression of Human Glucocorticoid Receptor Gene and Interaction of Nuclear Proteins with the Transcriptional Control Element*
We have identified sequences responsible for the expression of the human glucocorticoid receptor gene (GR gene) using a set of 5… 
Highly Cited
1995
Highly Cited
1995
Purification of the sequence‐specific transcription factor CTCBF, involved in the control of human collagen IV genes: subunits with homology to Ku antigen.
The common promoter region of the human collagen type IV genes COL4A1 and COL4A2 comprises a C5TC7 sequence (‘CTC box’) which is… 
Highly Cited
1993
Highly Cited
1993
Metastasis associated MTS1 and NM23 genes affect tubulin polymerisation in B16 melanomas: a possible mechanism of their regulation of metastatic behaviour of tumours.
The nm23 and mts1 genes are associated with the expression of the metastatic phenotype. We have shown previously that modulation… 
Highly Cited
1985
Highly Cited
1985
Structural analysis of TL genes of the mouse.
Three Tla region-specific probes have been generated from the BALB/c genomic cosmid clone C6.3. One probe, pTL1, corresponds to 3… 
Highly Cited
1984
Highly Cited
1984
Regulation of product formation during glucose or lactose limitation in nongrowing cells of Streptococcus lactis
Nongrowing cells of Streptococcus lactis in a pH-stat were dosed with sugar to allow fermentation at the maximum rate or were fed… 
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