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Ku autoantigen

Known as: Antigen, G22P1, Heterodimer, Ku, Ku 
An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa… Expand
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
Characterizing the functional overlap and mutagenic potential of different pathways of chromosomal double-strand break (DSB… Expand
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Review
2004
Review
2004
Ku is of central importance to DNA repair in eukaryotes. In addition, Ku has a key role in a number of other fundamental cellular… Expand
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Highly Cited
2001
Highly Cited
2001
The Ku heterodimer (Ku70 and Ku80 subunits) contributes to genomic integrity through its ability to bind DNA double-strand breaks… Expand
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Highly Cited
2001
Highly Cited
2001
DNA repair by nonhomologous end-joining (NHEJ) relies on the Ku70:Ku80 heterodimer in species ranging from yeast to man. In… Expand
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Highly Cited
1998
Highly Cited
1998
The DNA-end-joining reactions used for repair of double-strand breaks in DNA and for V (D)J recombination, the process by which… Expand
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Highly Cited
1996
Highly Cited
1996
Abstract The CBFβ subunit is the non-DNA-binding subunit of the heterodimeric core-binding factor (CBF). CBFβ associates with DNA… Expand
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Highly Cited
1993
Highly Cited
1993
The DNA-dependent protein kinase (DNA-PK) phosphorylates Sp1 and several other nuclear proteins. Here, we show that Sp1 and the… Expand
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Highly Cited
1992
Highly Cited
1992
The carboxyl-terminal domain of RNA polymerase II contains a tandemly repeated heptapeptide sequence. Previous work has shown… Expand
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Highly Cited
1990
Highly Cited
1990
HeLa cells contain a serine/threonine protein kinase (DNA-PK) that is strongly activated in vitro by low concentrations of double… Expand
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Highly Cited
1986
Highly Cited
1986
The mechanism of interaction between the Ku autoantigenic protein, a heterodimer of noncovalently linked 70,000- and 80,000… Expand
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