XRCC5 protein, human

Known as: X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 5 (Double-Strand-Break Rejoining), Ku86 autoantigen related protein-1, human, double-strand-break rejoining; Ku autoantigen, 80kDa protein, human 
X-ray repair cross-complementing protein 5 (732 aa, ~83 kDa) is encoded by the human XRCC5 gene. This protein is involved in both V(D)J recombination… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Background:Radiotherapy is central in the treatment of cervical cancer. The formation of DNA double-strand breaks is considered… (More)
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Highly Cited
2008
Highly Cited
2008
The role of reactive oxygen species (ROS) production on DNA damage and potentiation of fludarabine lethality by the histone… (More)
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2008
2008
UNLABELLED Early diagnosis of hepatocellular carcinoma (HCC) greatly improves its prognosis. However, the distinction between… (More)
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Highly Cited
2008
Highly Cited
2008
The DNA-dependent protein kinase (DNA-PK) complex is a serine/threonine protein kinase comprised of a 469-kDa catalytic subunit… (More)
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Highly Cited
2007
Highly Cited
2007
Ionizing radiation exposure results in the activation of several tyrosine kinase receptors that participate in radiation-induced… (More)
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2004
2004
An RNA-dependent association of Ku antigen with nuclear DNA helicase II (NDH II), alternatively named RNA helicase A (RHA), was… (More)
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2003
2003
Increased sensitivity to ionizing radiation (IR) has been shown to be due to defects in DNA double-strand break repair machinery… (More)
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2003
2003
Modulation of DNA repair represents a strategy to overcome acquired drug resistance of cells to genotoxic chemotherapeutic agents… (More)
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Highly Cited
2002
Highly Cited
2002
Ku86 plays a key role in nonhomologous end joining in mammals. Functional inactivation in rodents of either Ku86 or Ku70, which… (More)
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1996
1996
DNA ends are generated during double-strand-break repair and recombination. A p70-p86 heterodimer, Ku, accounts for the DNA end… (More)
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