DNA Helicases

Known as: DNA unwinding enzyme, Helicases, Helicase 
Helicases are a class of enzymes that utilize the energy of ATP hydrolysis to promote unwinding of 1.) RNA during transcription, splicing and… (More)
National Institutes of Health

Papers overview

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Review
2011
Review
2011
Interstrand crosslinks (ICLs) are highly toxic DNA lesions that prevent transcription and replication by inhibiting DNA strand… (More)
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Highly Cited
2008
Highly Cited
2008
A key cellular response to DNA double-strand breaks (DSBs) is 5'-to-3' DSB resection by nucleases to generate regions of ssDNA… (More)
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Review
2008
Review
2008
Helicases and remodeling enzymes are ATP-dependent motor proteins that play a critical role in every aspect of RNA and DNA… (More)
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Highly Cited
2006
Highly Cited
2006
The innate immune system senses viral infection by recognizing a variety of viral components (including double-stranded (ds)RNA… (More)
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Highly Cited
2005
Highly Cited
2005
The cellular protein retinoic acid-inducible gene I (RIG-I) senses intracellular viral infection and triggers a signal for innate… (More)
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Review
2003
Review
2003
RecQ helicases are highly conserved from bacteria to man. Germline mutations in three of the five known family members in humans… (More)
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Highly Cited
2002
Highly Cited
2002
Using in silico analysis we studied a novel family of repetitive DNA sequences that is present among both domains of the… (More)
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Highly Cited
2001
Highly Cited
2001
BRCA1 interacts in vivo with a novel protein, BACH1, a member of the DEAH helicase family. BACH1 binds directly to the BRCT… (More)
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Highly Cited
1995
Highly Cited
1995
The Bloom's syndrome (BS) gene, BLM, plays an important role in the maintenance of genomic stability in somatic cells. A… (More)
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Highly Cited
1989
Highly Cited
1989
In the course of systematic analysis of protein sequences containing the purine NTP-binding motif, a new superfamily was… (More)
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