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BLM protein, human

Known as: BLM, BLM Protein, Bloom syndrome protein, human 
Bloom syndrome protein (1417 aa, ~159 kDa) is encoded by the human BLM gene. This protein plays a role in DNA replication and cell division.
National Institutes of Health

Related topics

Related topics

16 relations
ATP HydrolysisAdenosine TriphosphatasesBLM geneBLM wt Allele
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Broader (1)

Bloom syndrome protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Interaction of replication protein A with two acidic peptides from human Bloom syndrome protein
Bloom syndrome protein (BLM) is one of five human RecQ helicases which maintain genomic stability. Interaction of BLM with… Expand
2018
2018
miR-522-3p Promotes Tumorigenesis in Human Colorectal Cancer via Targeting Bloom Syndrome Protein.
miR-522-3p is known to degrade bloom syndrome protein (BLM) and enhance expression of other proto-oncogenes, leading to… Expand
2017
2017
The bloom syndrome protein, BLM, inhibits homologous recombination by disrupting RAD51 nucleoprotein filaments
 
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2016
2016
Mapping replication dynamics in Trypanosoma brucei reveals a link with telomere transcription and antigenic variation
Survival of Trypanosoma brucei depends upon switches in its protective Variant Surface Glycoprotein (VSG) coat by antigenic… Expand
2011
2011
Structural and functional characterization of the N-terminal domain of human Rad51D.
  • Y. Kim, B. Choi
  • The international journal of biochemistry & cell…
  • 2011
    • Corpus ID: 22160458
Rad51D, one of five Rad51 paralogs, is required for homologous recombination and disruption of Holliday junctions with bloom… Expand
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2007
2007
Structural and functional analyses of disease-causing missense mutations in Bloom syndrome protein
Bloom syndrome (BS) is an autosomal recessive disorder characterized by genomic instability and the early development of many… Expand
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2006
2006
A positive involvement of RecQL4 in UV-induced S-phase arrest.
RecQL4 belongs to a family of conserved RECQ helicases that are important in maintaining chromosomal integrity. Human patients… Expand
Highly Cited
2003
Highly Cited
2003
Characterization and mutational analysis of the RecQ core of the bloom syndrome protein.
Bloom syndrome protein forms an oligomeric ring structure and belongs to a group of DNA helicases showing extensive homology to… Expand
2001
2001
Selective Cleavage of BLM, the Bloom Syndrome Protein, during Apoptotic Cell Death*
Bloom syndrome (BS) is an autosomal recessive disorder characterized by a high incidence of cancer and genomic instability. BLM… Expand
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Highly Cited
2001
Highly Cited
2001
Regulation and Localization of the Bloom Syndrome Protein in Response to DNA Damage
Bloom syndrome (BS) is an autosomal recessive disorder characterized by a high incidence of cancer and genomic instability. BLM… Expand
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