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KRAS gene

Known as: K-ras Genes, Oncogene K-Ras, C-KRAS 
Human Oncogene K-Ras is a mutated variant of KRAS2 Gene, which encodes two alternative isoforms of monomeric p21 K-RAS protein, a monomeric GTPase… 
National Institutes of Health

Related topics

Related topics

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12p12.1Adenocarcinoma of rectumAdenocarcinoma of the large intestineAmpulla of Vater Pancreatobiliary Type Adenocarcinoma

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KRAS wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Co-Treatment with Panitumumab and Trastuzumab Augments Response to the MEK Inhibitor Trametinib in a Patient-Derived Xenograft Model of Pancreatic Cancer1
Highly Cited
2013
Highly Cited
2013
High-throughput interrogation of PIK3CA, PTEN, KRAS, FBXW7 and TP53 mutations in primary endometrial carcinoma.
Highly Cited
2012
Highly Cited
2012
Driver mutations determine survival in smokers and never‐smokers with stage IIIB/IV lung adenocarcinomas
The authors previously demonstrated that never‐smokers with stage IIIB/IV nonsmall cell lung cancer (NSCLC) lived 50% longer than… 
2011
2011
Clinical characterization of patients with metastatic colorectal cancer depending on the KRAS status
This retrospective study investigated the clinical characteristics of patients with metastatic colorectal cancer (mCRC) depending… 
Highly Cited
2010
Highly Cited
2010
A KRAS-variant in ovarian cancer acts as a genetic marker of cancer risk.
Ovarian cancer (OC) is the single most deadly form of women's cancer, typically presenting as an advanced disease at diagnosis in… 
Highly Cited
2010
Highly Cited
2010
Tumor and Stem Cell Biology Cancer Research A Mouse Model of Melanoma Driven by Oncogenic KRAS
Authors' Pathology Institute of Note: Sup Research O Correspon Institute of ed Kingdo marais@icr 
1997
1997
Analysis of loss of heterozygosity and KRAS2 mutations in ovarian neoplasms: Clinicopathological correlations
The molecular events that give rise to ovarian epithelial neoplasms are not well understood. In particular, it is not known… 
Highly Cited
1996
Highly Cited
1996
Fine mapping of colon tumor susceptibility (Scc) genes in the mouse, different from the genes known to be somatically mutated in colon cancer.
The predisposition to colon cancer is multigenetically controlled in animals and probably also in humans. We have analyzed the… 
Highly Cited
1991
Highly Cited
1991
Mutations in the Kirsten-ras oncogene are common but lack correlation with prognosis and tumor stage in human pancreatic carcinoma.
Utilizing the polymerase chain reaction (PCR), we studied the presence and pattern of mutations in the Kirsten (Ki)-ras oncogene… 
Highly Cited
1986
Highly Cited
1986
A human gastric carcinoma contains a single mutated and an amplified normal allele of the Ki-ras oncogene.
The DNA from various human tumors and tumor cell lines was screened for the presence of mutated ras oncogenes with synthetic… 
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