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KRAS wt Allele

Known as: K-Ras 2A, K-RAS2B, C-K-RAS 
Human KRAS wild-type allele is located in the vicinity of 12p12.1 and is approximately 45 kb in length. This allele, which encodes GTPase KRas… Expand
National Institutes of Health

Papers overview

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2005
2005
Objective  To detect and analyse ki‐ras point mutations in colorectal adenomas and carcinomas in patients from Greece, where… Expand
Review
2005
Review
2005
Mutations in the Ki-ras and TP53 genes are the most frequently observed genetic alterations in colorectal cancer (CRC). Ki-ras… Expand
Highly Cited
2003
Highly Cited
2003
Background and aims: Mutant tumour derived DNA has been detected in the sera of colorectal cancer patients. We investigated if… Expand
2002
2002
PURPOSE Early detection of pancreatic cancer using molecular markers may improve outcome. Mutations of the ki-ras oncogene are… Expand
Review
2000
Review
2000
The 5′ flanking region of the C3(1) component of the rat prostate steroid binding protein (PSBP) has been used to successfully… Expand
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2000
2000
A differential susceptibility phenotype to the organotropic colon carcinogen azoxymethane (AOM) has been described in mice. The… Expand
Highly Cited
1994
Highly Cited
1994
The topographical distribution of a mutation provides insight into past patterns of tumor evolution. This approach was applied to… Expand
1988
1988
The proto-oncogenes have the capacity for conversion to an oncogene that is capable of inducing or maintaining the transformed… Expand
1987
1987
Protooncogenes have the ability to induce and/or maintain the transformed state when they are overly expressed or altered by… Expand
1986
1986
To investigate the possible involvement of proto-oncogenes in the regulation of cell differentiation and proliferation, their… Expand