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KRAS wt Allele
Known as:
K-Ras 2A
, K-RAS2B
, C-K-RAS
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Human KRAS wild-type allele is located in the vicinity of 12p12.1 and is approximately 45 kb in length. This allele, which encodes GTPase KRas…
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National Institutes of Health
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Related topics
Related topics
23 relations
12p12.1
Adenocarcinoma of ampulla of Vater
Adenocarcinoma of lung (disorder)
Ampulla of Vater Intestinal-Type Adenoma
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Broader (1)
KRAS gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Colorectal adenomas with a low frequency of ki‐ras mutations: a sample from a population with a low mortality rate from colorectal cancer
S. Kornaros
,
T. Liloglou
,
M. Politou
,
I. Elemenoglou
Colorectal Disease
2005
Corpus ID: 24143180
Objective To detect and analyse ki‐ras point mutations in colorectal adenomas and carcinomas in patients from Greece, where…
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Review
2005
Review
2005
Prognostic and predictive factors in colorectal cancer: Kirsten Ras in CRC (RASCAL) and TP53CRC collaborative studies.
A. Russo
,
V. Bazan
,
V. Agnese
,
V. Rodolico
,
N. Gebbia
Annals of Oncology
2005
Corpus ID: 8127334
Mutations in the Ki-ras and TP53 genes are the most frequently observed genetic alterations in colorectal cancer (CRC). Ki-ras…
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Highly Cited
2003
Highly Cited
2003
A prospective study of circulating mutant KRAS2 in the serum of patients with colorectal neoplasia: strong prognostic indicator in postoperative follow up
B. Ryan
,
F. Lefort
,
+4 authors
D. Kelleher
Gut
2003
Corpus ID: 26777485
Background and aims: Mutant tumour derived DNA has been detected in the sera of colorectal cancer patients. We investigated if…
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2002
2002
Low sensitivity of the ki-ras polymerase chain reaction for diagnosing pancreatic cancer from pancreatic juice and bile: a multicenter prospective trial.
L. Trümper
,
M. Menges
,
+8 authors
M. Pfreundschuh
Journal of Clinical Oncology
2002
Corpus ID: 39362604
PURPOSE Early detection of pancreatic cancer using molecular markers may improve outcome. Mutations of the ki-ras oncogene are…
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Review
2000
Review
2000
The C3(1)/SV40 T-antigen transgenic mouse model of mammary cancer: ductal epithelial cell targeting with multistage progression to carcinoma
Jeffrey E. Green
,
M. Shibata
,
+11 authors
C. Couldrey
Oncogene
2000
Corpus ID: 22266533
The 5′ flanking region of the C3(1) component of the rat prostate steroid binding protein (PSBP) has been used to successfully…
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1995
1995
Overexpression of protein kinase C beta 1 in the SW480 colon cancer cell line causes growth suppression.
D. Goldstein
,
A. Cacace
,
I. Weinstein
Carcinogenesis
1995
Corpus ID: 11178766
Using a retroviral vector system we have established derivatives of the E8 subclone of the human colon cancer cell line SW480…
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Highly Cited
1994
Highly Cited
1994
c-k-ras and p53 mutations occur very early in adenocarcinoma of the lung.
Z. H. Li
,
J. Zheng
,
L. Weiss
,
D. Shibata
American Journal of Pathology
1994
Corpus ID: 10178607
1988
1988
Aberrant expression of the K-ras proto-oncogene in B-cell malignancies.
J. Lee
,
M. Talpaz
,
R. Walters
,
J. Gutterman
,
M. Blick
Hematologic pathology
1988
Corpus ID: 37175163
The proto-oncogenes have the capacity for conversion to an oncogene that is capable of inducing or maintaining the transformed…
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1987
1987
Aberrant oncogene expression in uncultured human sarcoma and melanoma.
D. Shin
,
V. Gupta
,
+4 authors
M. Blick
Anticancer Research
1987
Corpus ID: 45850034
Protooncogenes have the ability to induce and/or maintain the transformed state when they are overly expressed or altered by…
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1986
1986
Sequential expression of proto-oncogenes during a mouse erythroleukemia cell differentiation.
K. Todokoro
,
Y. Ikawa
Biochemical and Biophysical Research…
1986
Corpus ID: 27279233
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