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KLK3 gene

Known as: KALLIKREIN-RELATED PEPTIDASE 3, KALLIKREIN 3, APS 
This gene is involved in the hydrolysis of high molecular mass seminal vesicle protein, resulting in the liquefaction of seminal coagulum.
National Institutes of Health

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Related topics

6 relations
HydrolysisKLKB1 geneKLKB1 wt AlleleProstate-Specific Antigen

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KLK3 wt Allele

Papers overview

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2018
2018
Enhancing Molecular Promiscuity Evaluation Through Assay Profiles
The growing amount of heterogeneous bioactivity data requires effective strategies to assess the promiscuity/selectivity of small… 
2014
2014
Kallikreins are involved in an miRNA network that contributes to prostate cancer progression
Abstract MicroRNAs (miRNAs) are short RNA nucleotides that negatively regulate their target genes. They are differentially… 
2012
2012
Association between KLK3 rs2735839 G/A Polymorphism and Serum PSA Levels in Japanese Men
Objectives: To clarify the association of kallikrein-related peptidase 3 (KLK3) rs2735839 G/A polymorphism with serum prostate… 
Review
2008
Review
2008
Development of peptides specifically modulating the activity of KLK2 and KLK3
Abstract The prostate produces several proteases, the most abundant ones being kallikrein-related peptidase 3 (KLK3, PSA) and… 
2007
2007
Recombinant prostate-specific antigen proaerolysin shows selective protease sensitivity and cell cytotoxicity
Native proaerolysin is a channel-forming bacterial protoxin that binds to cell-surface receptors and then is activated by furin… 
2006
2006
In silico identification and Bayesian phylogenetic analysis of multiple new mammalian kallikrein gene families.
2000
2000
Expression, purification, and characterization of deglycosylated human pro-prostate-specific antigen.
Wild-type and deglycosylated forms of human prostate-specific antigen were expressed in Chinese hamster ovary (CHO) cells as… 
Highly Cited
1999
Highly Cited
1999
Localization of a New Prostate-specific Antigen-related Serine Protease Gene, KLK4, Is Evidence for an Expanded Human Kallikrein Gene Family Cluster on Chromosome 19q13.3–13.4*
The human tissue kallikrein (KLK) family of serine proteases, which is important in post-translational processing events… 
1999
1999
Western Blotting Analysis of Antibodies to Prostate-Specific Antigen: Specificities for Prostate-Specific Antigen and Prostate-Specific Antigen Fragments
Approximately 40% of the prostate-specific antigen (PSA) purified from seminal fluid comprises cleaved or fragmented forms of PSA… 
Review
1991
Review
1991
Regulation of cystatin C activity by serine proteinases.
The effect of four human serine proteinases on the human cysteine proteinase inhibitor, cystatin C, has been studied in vitro… 
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