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KLK3 wt Allele

Known as: PSA, APS, Kallikrein 3, (Prostate Specific Antigen) wt Allele 
Human KLK3 wild-type allele is located in the vicinity of 19q13.41 and is approximately 6 kb in length. This allele, which encodes prostate-specific… 
National Institutes of Health

Related topics

Related topics

10 relations
19q13.41Androgen Receptor Regulation PathwayAntigen Presentation PathwayHomo sapiens

Broader (1)

KLK3 gene

Papers overview

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Review
2007
Review
2007
Autoimmune polyendocrine syndrome type 1 in Norway: phenotypic variation, autoantibodies, and novel mutations in the autoimmune regulator gene.
CONTEXT The autoimmune polyendocrine syndrome type I (APS I) is a rare disease that previously was difficult to diagnose… 
2006
2006
Effect of testosterone administration on serum and urine kallikrein concentrations in female-to-male transsexuals.
BACKGROUND Concentrations of human tissue kallikreins (hKs), a group of 15 secreted serine proteases found in many tissues, are… 
2006
2006
Human kallikrein 3 (prostate specific antigen) and human kallikrein 5 expression in salivary gland tumors.
The human kallikrein 5 protein (hK5) is expressed in many normal tissues, most notably in skin, breast, salivary gland and… 
Review
2002
Review
2002
Human tissue kallikreins: a family of new cancer biomarkers.
Kallikreins are a subgroup of the serine protease enzyme family. Until recently, it was thought that the human kallikrein gene… 
Highly Cited
2001
Highly Cited
2001
Insulin-like growth factor binding proteins (IGFBPs) as potential physiological substrates for human kallikreins hK2 and hK3.
Insulin-like growth factors (IGFs) are important growth regulators of both normal and malignant prostate cells. Their action is… 
1999
1999
Characterization and processing of prostate specific antigen (hK3) and human glandular kallikrein (hK2) secreted by LNCaP cells
Prostate specific antigen (PSA, hK3) in serum is predominantly complexed to α-1-antichymotrypsin (ACT), but a minor fraction… 
1998
1998
Prostate-specific antigen (hK3) and human prostatic glandular kallikrein (hK2) in the detection of early stage human prostate cancer.
1997
1997
Detection of prostate cancer cells circulating in peripheral blood by reverse transcription-PCR for hKLK2.
Two of the human tissue kallikrein family, hK2 and hK3 (prostate-specific antigen), are primarily produced by the prostatic… 
1997
1997
Human kallikrein hK2 has low kininogenase activity while prostate-specific antigen (hK3) has none.
Highly Cited
1996
Highly Cited
1996
Potential involvement of kallikrein hK2 in the hydrolysis of the human seminal vesicle proteins after ejaculation.
We have recently demonstrated in liquefied human seminal plasma the presence of the novel kallikrein hK2 in association with… 
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