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KLKB1 gene

Known as: PKK, Kallikrein B, Plasma (Fletcher Factor) 1 Gene, KLK3, FORMERLY 
This gene plays a role in proteolytic processing.
National Institutes of Health

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Blood coagulationHydrolysisKLK3 geneKLK3 wt Allele

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KLKB1 wt Allele

Papers overview

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1985
1985
Interaction of factor XII, high-molecular-weight (HMW) kininogen and prekallikrein with sulfatide: analysis by fluorescence polarization.
The interaction of high-molecular-weight (HMW) kininogen, Factor XII and prekallikrein with sulfatide was studied by fluorescence… 
1983
1983
Immunologic studies of human coagulation factor XI and its complex with high molecular weight kininogen
Coagulation factor XI was purified from human plasma using ion-exchange chromatography and affinity chromatography on high… 
1983
1983
Plasma prekallikrein: quantitative determination by direct activation with Hageman factor fragment (beta-XIIa).
This report describes a plasma prekallikrein assay which, unlike methods that employ contact activation, is not affected by the… 
1982
1982
Hypotensive effects of plasma protein fraction. The relation between prekallikrein activator, bradykinin generation, and blood pressure in an animal model.
In a rat model, the relationship between the activity of PKA in human PPFs, the changes in arterial BK concentration, and the… 
1982
1982
Mechanism of surface-mediated activation of bovine factor XII and plasma prekallikrein.
1981
1981
Factors XI and XII and prekallikrein in sick and healthy premature infants.
PREMATURE infants have markedly decreased levels of factors XI and XII and prekallikrein, which play an important part in the… 
1980
1980
Kallikrein and Renin in the Membrane Fractions of the Rat Kidney
SUMMARY Plasma membrane (PM) and endoplasmic reticulum (ER) enriched fractions were isolated from the homogenized rat kidney… 
1979
1979
Determination of prekallikrein in plasma by means of a chromogenic tripeptide substrate for plasma kallikrein.
A method for plasma prekallikrein determination utilizing a chromogenic tripeptic substrate is presented. The method has a good… 
1978
1978
Deficiency of factor XII-dependent plasminogen proactivator in prekallikrein-deficient plasma.
Normal human plasma contains a factor XII (Hageman factor)-dependent plasminogen proactivator in its gamma globulin fraction. On… 
1972
1972
Bovine prekallikrein activator with functional activity as Hageman factor.