KLKB1 gene

Known as: PKK, Kallikrein B, Plasma (Fletcher Factor) 1 Gene, KLK3, FORMERLY 
This gene plays a role in proteolytic processing.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Recent studies indicate that the plasma contact system plays an important role in thrombosis, despite being dispensable for… (More)
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Highly Cited
2008
Highly Cited
2008
CONTEXT The genetic causes of deep vein thrombosis (DVT) are not fully understood. OBJECTIVE To identify single-nucleotide… (More)
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Highly Cited
2004
Highly Cited
2004
Identifying regions of the human genome that have been targets of natural selection will provide important insights into human… (More)
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Highly Cited
2002
Highly Cited
2002
Investigations were performed to define the factor XII (FXII) binding site(s) on cultured endothelial cells (HUVECs). Biotin- or… (More)
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Highly Cited
1997
Highly Cited
1997
The urokinase receptor (uPAR) binds urokinase-type plasminogen activator (u-PA) through specific interactions with uPAR domain 1… (More)
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Highly Cited
1996
Highly Cited
1996
Previous work has demonstrated that most strains of the human pathogen Streptococcus pyogenes bind kininogens through M protein… (More)
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Highly Cited
1983
Highly Cited
1983
Patients with hereditary angioedema lack C-1 inhibitor, a plasma alpha 2-glycoprotein that inhibits both the proteolytic action… (More)
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Highly Cited
1978
Highly Cited
1978
The mechanism by which negatively charged substances such as celite, kaolin, or ellagic acid contribute to the surface-dependent… (More)
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Highly Cited
1977
Highly Cited
1977
Factor XI and high molecular weight kininogen were found associated in normal human plasma at mol wt 380,000 as assessed by gel… (More)
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1972
1972
Human plasma kallikrein has been shown to directly and selectively attract human neutrophils from a mixed leukocyte population… (More)
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